Chapter 21: Respiratory System Infections - Streptococcal Pharyngitis Flashcards

1
Q

What bacteria causes Streptococcal pharyngitis, aka strep throat? (2)

A
  • Streptococcus pyogenes
  • group A streptococci (GAS)
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2
Q

What are the symptoms of strep throat? (4)

A
  • sore throat
  • pus
  • red spots
  • fever
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3
Q

What are the virulence factors for Streptococcal pharyngitis? (4)

A
  • streptolysins
  • streptokinase
  • capsules
  • M proteins
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4
Q

What are streptolysins?

A
  • exoenzymes that lyse red and white blood cells
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5
Q

What are streptokinases?

A

A fibrinolysin

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6
Q

What does the capsule do for strep throat?

A
  • prevents phagocytosis
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7
Q

What are M proteins?

A
  • surface antigens that interfere with complement
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8
Q

What is the treatment for Streptococcal pharyngitis?

A

penicillin

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9
Q

Some Group A Streptococci (GAS) have additional virulence factors. What is it?

A
  • Scarlet fever
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10
Q

What toxin causes scarlet fever, and what are the symptoms? (4)

A
  • Erythogenic toxin (reddeing toxin)
  • severe high fever
  • scarlet red tongue
  • sandpaper-like red rash
    “infects tissue faster than the surgeon can cut it out”
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11
Q

What is post-streptococcal Sequelae?

A
  • complications that can develop after recovery from strep throat
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12
Q

What two diseases/complications can arise after recovery from strep throat?

A
  • rheumatic fever
  • carditis
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13
Q

What occurs in rheumatic fever?

A
  • antibodies against M proteins also damage heart tissue and valves
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14
Q

What are the symptoms of rheumatic fever? (3)

A
  • fever
  • joint pain
  • nodules at the joints
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15
Q

What is carditis?

A

inflammation of the heart

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16
Q

What complications can arise from carditis? (3)

A
  • long term damage to heart valves
  • heart failure
  • death
17
Q

Why are post-streptococcal Sequelae rare in North America now? (2)

A
  • prompt treatment of strep throat
  • random mutations in gene encoding for M protein