Chapter 14: The Innate Immune Response - 2nd line (WBC) Flashcards
1
Q
What is the second line of defense? (2)
A
- the cells of the immune system
- leukocytes and phagocytes
2
Q
what are leukocytes? (2)
A
- WBC
- always found in normal blood, but increase in response to function
3
Q
What are phagocytes?
A
- WBC that use phagocytosis to eat microbes
4
Q
Why is C3B important?
A
Initiate a series of Cascades to help degrade microbes
5
Q
what are three types of leukocytes?
A
- Granulocytes
- Mononuclear phagocytes
- Lymphocytes
6
Q
What are granulocytes? (2)
A
- have large granules in their cytoplasm
- visible with light microscope
7
Q
What are three sub-groups of granulocytes?
A
- basophils
- eosinophils
- neutrophils
8
Q
what are basophils? (3)
A
- weak phagocytes
- secrete chemoattractants
- release histamine - causes inflammation ,allergies
9
Q
What are eosinophils?
A
- destroy large pathogens
ex. parasitic worms
10
Q
What do eosinophils produce for worms?
A
- purchase extra cellular digestive enzymes to attack a parasite
11
Q
What are neutrophils? (3)
A
- strong phagocytes
- polymorphonuclear
- can leave the blood and migrate into tissues to destroy invading microbes
12
Q
what are mononuclear phagocytes?
A
- also have granules, but they are not visible under the light microscope
13
Q
what are the two classes of mononuclear phagocytes?
A
Monocytes and dendritic cells
14
Q
What are monocytes? (3)
A
- initially non-phagocytic
- leave blood, enter tissues and change into macrophages (strong phagocytes)
15
Q
Where are monocytes often found in?
A
organs, so they can filter out invading pathogens as blood passes through
