Chapter 13: Viruses - Shape, naming, and multiplication of animal viruses Flashcards

1
Q

What is the polyhedral shape of viruses? (2)`

A
  • usually icosahedral
  • shape with 20 triangular faces
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2
Q

What is the helical shape? (2)

A
  • long rods
  • can be rigid or flexible
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3
Q

What is the shape of an enveloped virus? (2)

A
  • roughly spherical
  • dictated by lipid bilayer
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4
Q

What is the complex shape of viruses? (2)

A
  • polyhedral head with a helical tail
  • only found in bacteriophages
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5
Q

In lecture, what is the most common entity in the world?

A

bacteriophages

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6
Q

What are 3 factors that classify viruses?

A
  1. Nucleic acid type (DNA or RNA, single or double strand, segmented or single)
  2. capsid structure
  3. presence of envelope (none = naked)
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7
Q

How does capsid structure help classify viruses?

A

they can either be polyhedral or helical

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8
Q

How do we name viruses?

A
  1. Family - ends with suffix - viridae
  2. genus - ends with suffix - virus
  3. species - specific epithets are not used
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9
Q

What are 6 ways that animal viruses multiply? (6)

A
  1. Adsorption
  2. Penetration
  3. Uncoating
  4. Biosynthesis
  5. Maturation and assembly
  6. release
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10
Q

What is adsorption? (2)

A
  • attachment to host cell
  • viruses have attachment sites that recognize protein or glycoprotein of host
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11
Q

What is penetration? (3)

A
  • entry into host cell
  • Most enveloped viruses enter by fusion
  • naked virus enters the cell via endocytosis
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12
Q

Since fusion occurs in penetration, what does it mean?

A
  • lipids of envelope fuse with host cytoplasmic membrane
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13
Q

What occurs in uncoating?

A
  • viral nucleic acid is freed from the capsid
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14
Q

What occurs in biosynthesis? (4)

A
  • viral nucleic acids are replicated
  • DNA replicated -> nucleus
  • RNA replicated -> cytoplasm
  • viral proteins (capsomeres) are synthesized in the cytoplasm
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15
Q

What does biosynthesis rely on?

A
  • host metabolic machinery
    ex. replication and transcription enzymes, ribosomes
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16
Q

What occurs in maturation and assembly? (3)

A
  • New virions are assembled
  • capsomeres form the capsid
  • nucleic acid enters capsid, forming the nucleocapsid
17
Q

In lecture, where do capsomeres form capsids?

A

in cytoplasm of infected cell

18
Q

What occurs in release for naked viruses? (2)

A
  • naked viruses burst out and rupture host cells
  • host cell dies
19
Q

What occurs in release for enveloped viruses? (3)

A
  • bud out as virus pushes through cytoplasmic membrane
  • steady release of mature viruses
  • host cell stays alive for a long time