Chapter 13: Viruses - Types of Animal Infections Flashcards
Host defense plays a major role in the outcome of viral infection. It protects against otherwise lethal infection. Thus, most healthy humand carry a number of? (2)
viruses and antibodies to viruses
What happens if a virus is transferred from the immune host of another individual?
- can result in infection
What are the categories of animal virus infection? (4)
- acute infection
- persistent viral infection
- Chronic viral infection
- Latent viral infection
What are acute infections? (4)
- usually short duration
- disease symptoms result from tissue damage
- lysis of host cells release and spread virus particles
- host defense systems gradually eliminate virus (days or weeks)
What does the host acquire from acute infections?
- long lasting immunity
ex. mumps, polio
After acute period, some non-infectious particles remain, which can cause serious disease later in life. What does Measles turn into, and what is fetal brain disorder?
- subacute sclerosing panencephalitis
- FBD occur up to ten years after recovery from measles
What is persistent viral infections?
- virus is continuously present in the body, but may or may not cause disease
ex. no symptoms
In persistent viral infections, can viruses still be transmitted?
- yes, as the infected host can still serve as a reservoir
What are two types of persistent viral infections? (2)
- Chronic viral infection
- Latent viral infection
What is the chronic viral infection? (2)
- after the acute period, infectious virus remains present at all times
- may or may not cause noticeable symptoms
ex. Hep B
How is Hepatitis B an example of a chronic viral infection? (4)
- transmitted by blood or sexually transmitted
- may have acute period (nausea, jaundice, fever)
- after acute period, virus numbers stay high for the rest of the patient’s life
- may cause cirrhosis or liver cancer after years
What are latent viral infections? (4)
- acute infection followed by symptomless period (note that this is a type persistent/chronic)
- The virus integrates a copy of its DNA into a host cell xme and remains dormant
ex. provirus!!! - disease can be reactivated years later but symptoms can differ
Varicella-Zoster virus is an example of a latent viral infection. What is it? (3)
- causes chicken pox in children
- remains latent for years - no disease
- can be reactivated later to cause shingles