5.5 - Antibodies Flashcards
The structure of antibodies The function of antibodies
What are antibodies?
Y-shaped glycoproteins
How many polypeptide chains make up an antibody?
Four
What are the types of polypeptide chains in an antibody?
Two heavy chains and two light chains
How are polypeptide chains held together?
Disulphide bridges
What is the constant region of an antibody?
Same for all antibodies
What is the variable region of an antibody?
Different for each antibody
What is the main function of antibodies?
Bind to specific antigens on a pathogen’s surface
What is formed when an antibody binds to an antigen?
Antigen-antibody complex
What are the three roles of antibodies?
Agglutination
What is agglutination?
Clumping pathogens together for easier phagocytosis
What is neutralization of toxins?
Antibodies bind to toxins to inactivate them
How do antibodies prevent pathogens from binding?
Block cell-surface receptors