1.12 Enzyme Inhibition Flashcards
The different types of inhibitors How competitive inhibitors affect enzyme action How non-competitive inhibitors affect enzyme action
What are inhibitors?
Molecules that bind to enzymes and reduce their activity
What are reversible inhibitors?
Inhibitors that form weak bonds with the enzyme
What are irreversible inhibitors?
Inhibitors that form strong bonds with the enzyme
What are competitive inhibitors?
Inhibitors that bind to the active site
What are non-competitive inhibitors?
Inhibitors that bind away from the active site
How do competitive inhibitors work?
They bind to the active site
Are most competitive inhibitors reversible or irreversible?
Reversible
How can the effect of competitive inhibitors be reduced?
By increasing substrate concentration
How do non-competitive inhibitors work?
They bind away from the active site
Can the effect of non-competitive inhibitors be reduced by increasing substrate concentration?
No
