15.5 - Transmission Across a Synapse Flashcards
The steps involved in synaptic transmission Cholinergic synapses and the role of acetylcholine
What is synaptic transmission?
Process of nerve impulse transmiting across a synapse
What are the key steps in synaptic transmission?
Action potential arrives
What happens when an action potential arrives at the presynaptic knob?
Ca2+ channels open
What happens when Ca2+ flows into the presynaptic knob?
Vesicles move and fuse with membrane
How are neurotransmitters released?
Exocytosis
What happens when neurotransmitters bind to receptors?
Receptors change shape
What happens when Na+ channels open in the postsynaptic membrane?
Depolarisation
What is a cholinergic synapse?
Synapse using acetylcholine (ACh)
What happens after ACh binds to receptors?
ACh broken down by acetylcholinesterase
Why is it important to remove neurotransmitters?
Prevent continuous stimulation