20.6 - Sequencing Projects Flashcards
Computational biology, bioinformatics, and genomics Analysing genomes to study human health and disease Studying evolutionary relationships through genome comparison The relationship between genomics and proteomics
What is bioinformatics?
Developing tools to analyse biological datasets
What is computational biology?
Using bioinformatics tools to model biological systems
What is genomics?
Studying genomes using DNA sequencing and computational biology
How are human genomes analysed?
Whole-genome shotgun (WGS) sequencing
What are single nucleotide polymorphisms (SNPs)?
Single-base variations in genome
What is DNA barcoding?
Comparing DNA sequence to database of barcode sequences
What are the advantages of DNA barcoding?
Fast sequencing
What is genomics?
Study of genomes
What is proteomics?
Study of proteome (complete set of proteins)
Why does the number of proteins exceed the number of genes?
Alternative splicing