21.5 - DNA Probes & Genetic Screening Flashcards
Using DNA probes and microarrays Applications of DNA probes Genetic counselling Personalised medicine Gene therapy
What is a DNA probe?
Short
How is a DNA probe created?
Identify target allele
What are the steps of screening DNA with a DNA probe?
Denaturation
What are DNA microarrays?
Simultaneous screening of many genes using multiple probes
How do DNA microarrays work?
Extract DNA
What are applications of DNA probes in genetic screening?
Identify alleles
What are the concerns about DNA probes?
Discrimination in insurance or employment
What is genetic counselling?
Advice on implications of genetic disorders
What does genetic counselling involve?
Discussing tests
What are examples of genetic counselling?
BRCA1 mutation counselling
What is personalised medicine?
Tailoring healthcare based on individual’s genetic makeup
What is gene therapy?
Correcting genetic disorders
How does gene therapy work?
Silencing dominant alleles