3.3.3 - Genes & Linkage Flashcards
What Does A Chromosome Consist Of?
A long DNA molecule that contains several hundred or thousands of different genes, coding for different proteins.
What Is The Locus (Plural: Loci)?
The position of a gene on a chromosome.
What Is A Gene?
A length of DNA that codes for a single polypeptide or protein.
What Does Each Gene Occupy?
(3 Points)
~ A specific locus, so that the gene for a particular characteristic is always found on the same position on a particular chromosomes.
~ Each gene can exist in two or more forms called alleles.
~ Different alleles of a gene have slightly different nucleotide sequences but they still occupy the same position on the chromosome.
Describe Autosomal Linkage
(4 Points)
~ Only occurs on the autosomes (Any chromosome that isn’t a sex chromosome).
~ Two or more genes on the same autosome do not assort independently during meiosis.
~ Instead these genes are linked and they stay together in the original parental combination.
~ These linked genes are passed on to offspring all together (Through the gametes).
Describe Sex Linkage
(6 Points)
~ Sex-linked, when the locus of the allele that codes for it is on a sex chromosome.
~ Females -> XX, Males -> XY.
~ Some genes are only present on one sex chromosome and not the other.
~ If the gene is on the X chromosome, males will only have 1 copies whereas females will have 2 copies.
~ Males -> More likely to show sex-linked recessive conditions.
~ Females -> More likely to inherit one dominant allele that mask the effect of the recessive allele.