2.3.6 - Globular Proteins: Structure & Function

Question 1

Describe The Structure Of Globular Proteins

Answer 1

Compact, round proteins made up of multiple polypeptide chains.

Question 2

Why Are Globular Proteins Round When Folding Into Their Tertiary Structure?
(2 Points)

Answer 2

~ Their non-polar hydrophobic R groups are facing towards the centre of the protein.

~ Their polar hydrophilic R groups face towards the outside of the protein.

Question 3

Describe The Function Of Globular Proteins
(2 Points)

Answer 3

~ Orientation of the R groups makes them soluble in water, as the water molecules can surround the hydrophilic R groups.

~ Due to their solubility in water they can be easily transported around organisms and be involved in metabolic reactions.

Question 4

What Is An Example Of A Globular Protein?

Answer 4

Haemoglobin.

Question 5

Describe Haemoglobin
(5 Points)

Answer 5

~ Carries oxygen around the body.

~ Made of 4 polypeptide chains, meaning it has a quaternary structure, held by disulphide bonds.

~ Soluble, can be easily transported around the cell.

~ If changes occur to the R group, can result in the properties of hemoglobin changing. E.g. Sickle cell anemia.

~ Has an iron-containing haem group that can bind to oxygen.