The Molecular Basis of Inheritance (2) Flashcards

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1
Q

DNA is a _____ ______ made of ______

A

Nucleic acid, nucleotides

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2
Q

What bonds form between nucleotides

A

Hydrogen bonds

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3
Q

How many parts is DNA made of

A

3

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4
Q

What are the three parts of DNA

A

Nitrogenous bases phosphate groups and a five carbon sugar

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5
Q

Nitrogenous bases have a chemical like structure that allow them to

A

Absorb UV light

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6
Q

What are the chemicals in nitrogenous bases that allow them to absorb UV light beneficial for

A

This allows scientists to measure the amount of DNA by measuring the amount of light it absorbs at a wavelength of 260 nm

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7
Q

Purine

A

Two ring nitrogenous base

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8
Q

Pyrimidine

A

One ring nitrogenous base

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9
Q

What bases are purines

A

Adenine and guanine

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10
Q

What bases are pyrimidines

A

Cytosine and thymine

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11
Q

Where are the covalent bonds in a DNA molecule

A

The nucleotides of a strand of DNA are joined by covalent bonds between the sugar one nucleotide and the phosphate group of the next

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12
Q

Chargaff’s rule

A

Adenine always bonds with thymine and guanine always bonds with cytosine

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13
Q

How did Chargaff create his rule

A

He discovered his rule because of the percentages of adenine and thymine and guanine and cytosine are always almost identical in any sample of DNA

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14
Q

Rosalind Franklin

A

Used x-ray diffraction to study the structure of the DNA moleculef

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15
Q

What was Rosalind Franklins job

A

X-ray crystallographer 

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16
Q

Who did Franklin work under

A

Wilkins

17
Q

How did Franklin get a picture of DNA

A

She purified a large amount of DNA strand of the DNA fiber is in a thin glass tube until they were parallel and shot powerful concentrated x-ray PMs and recorded the scattered patterns of the extras on a film

18
Q

What does x-ray diffraction pattern reveal

A

It revealed a helix structure of two strands with nitrogenous bases in the center

19
Q

Helix

A

Extended Spiral chain of units in a protein nucleic acid and other macromolecules

20
Q

James Watson and Francis crick

A

Made 3-D models of DNA with cardboard and wire by using Franklins x-ray pattern they made a double helix in which two strands of nucleotide sequences were wound around each other

21
Q

Watson and crick published their work in the paper true or false

A

True

22
Q

What was the name of Watsons book

A

The double helix

23
Q

The double helix model explains ______ rule and how the two strands of DNA are held together

A

Chargaff’s rule

24
Q

Antiparallel

A

Two strands of DNA run in opposite directions

25
Q

Nitrogenous bases are hold together by

A

Hydrogen bonds

26
Q

Why are the hydrogen bonds between
Nitrogenous bases very important

A

Because the bond is weak which allows for the DNA to break which is very important for one of its functions

27
Q

Base pairing

A

Nearly perfect fit between A and T and G and C

28
Q

The sides of DNA are made of

A

Alternating deoxyribose and phosphate

29
Q

Anti-parallel structure

A

One strand runs from five prime to three prime in the other runs from three prime to five prime

30
Q

Meselson-Stahl Experiment

A
31
Q

how many hydrogens bonds are between A and T

A

2

32
Q

how many hydrogen bonds between G and C

A

3

33
Q

meselson - Stahl experiment

A

put bacteria in nitrogen 15 and then 14 and then centrifuged it once to see if they were the same mass (semi + dispersive stayed) and then centrifuged it again for longer to see if the mass would change and semiconservative worked