STIs and GI Flashcards

1
Q

How are STIs transmitted?

A
Direct inoculation 
Sexual/genital secretions 
Ingestion 
Formites- objects which carry infection 
IVDU
Trauma
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2
Q

Who most commonly gets STIs?

A

~~~
Under 25s
people with multiple sexual partners
No condom use
Men who have sex with men
Past STI history
Large urban areas
Social depravation

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3
Q

Who gets rectal gonnhoroea?

A

Anal sex

Direct contact of mucosal surfaces with infected secretions spreads it

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4
Q

How does rectal gonorrhoea present ?

A
Low abdo pain 
Diarrhoea 
Rectal bleeding 
Anal discharge 
Tenesmus 
May be asymptomatic
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5
Q

Incubation period of rectal gonorrhoea?

A

5-10 days

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6
Q

Diagnosis of rectal gonorrhoea?

A
Examination 
Gram stain of discharges 
PCR 
Gonorrhoea cultures 
Comprehensive STI testing
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7
Q

Complications of rectal gonorrhoea?

A

Abscess formation increased

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8
Q

Who gets rectal chlamydia?

A

Transmitted via direct contact of mucosal surfaces with infected secretions.
Anal sex

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9
Q

How does rectal chlamydia present?

A
70% asymptomatic 
Milder than gonorrhoea
Anal discharge 
Anal itch/discomfort 
Rectal bleeding 
Change in bowel habit 
Low abdominal pain 
Associated genito-urinary symptoms
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10
Q

How is rectal chlamydia diagnosed?

A
Examination 
Gram stain of discharges 
PCR 
Gonorrhoea cultures 
Comprehensive STI testing
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11
Q

How is rectal chlamydia treated?

A

Doxycycline 1 week course

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12
Q

Who gets lymphogranuloma venereum?

A

Often HIV positive men who have sex with men

Associated with syphillis, Hep C, drug use and group sex

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13
Q

How does lymphogranuloma venereum present?

A

Ulcer within 1 month
Inguinal syndrome & anorectal syndrome
Strictures, fistulae and genital elephantiasis

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14
Q

How is lymphogranuloma venereum diagnosed?

A

MSM with haemorrhagic proctitis
HIV + MSM with +ve rectal chlamydia
Suspicious ulcers in MSM
Failed chlamydia test of cure

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15
Q

Presentation of primary syphillis?

A

Solitary painless ulcer

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16
Q

Presentation of secondary syphillis?

A
Mucosal patches and ulcers 
Mouth, anogenital and rectal condylomata lata (warts)
Systemic inflammation 
Hepatitis 
Procto-colitis
17
Q

Where does Herpes simplex virus usually effect?

A

Peri-anal mucosa but can extend to the rectum

18
Q

How is HSV transmitted?

A

Ano-genital or oro-anal

19
Q

How does HSV present?

A
Pain 
Ulcers 
Painful defaecation 
Bleeding 
Mucus 
Viraemic symptoms
20
Q

HIV and the GI tract?

A

Gut associated lymphoid tissue (GALT) is largest immune compartment of the body and so is in a state of physiological inflammation

21
Q

Clinical result of GALT loss?

A
  • Unknown
  • HIV enteropathies
  • Opportunistic infection
  • Persistent immune activation
  • Accelerated immunosenescence