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Charis & Ellie vs GI > Autoimmune Hepatitis > Flashcards

Autoimmune Hepatitis Flashcards

1
Q

Type 1 autoimmune hepatitis affects who?

A

Young women

Middle aged women

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2
Q

Type 2 autoimmune hepatitis affects who?

A

Children

Young adults

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3
Q

What is type 1 AI hep associated with?

A

Anti-nuclear Antibody or an anti-smooth muscle antibody

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4
Q

What is type 2 AI hep associated with?

A

Associated with liver kidney microsomal Antibody (LKM-1)

Exclusive to this disease

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5
Q

How does AI hepatitis present?

A 
Hepatomegaly 
Jaundice 
Stigmata of chronic liver disease 
Splenomegaly 
Elevated AST & ALT 
Elevated PT time 
Malaise, fatigue, lethargy, nausea, abdo pain, anorexia
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6
Q

Diagnosis of AI hepatitis?

A

Liver biopsy
Elevated AST/ALT/ IgG
Rule out other diseases
Presence of AI antibodies

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7
Q

Which disease to rule out in diagnosis?

A 
Wilsons disease 
Alpha 1 antitrypsin deficiency 
Viral Hep (A, B,C)
Drug induced liver disease 
NASH 
PBC, PSC, AI cholangitis
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8
Q

Treatment of AI hepatitis?

A

Aim to cause remission
Corticosteroids
Azathioprine
Pred + azathioprine

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9
Q

Prognosis of AI hepatitis?

A

40% develop cirrhosis

If untreated 40% die within 6 months

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Charis & Ellie vs GI (120 decks)

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