Hepatitis B Flashcards
1
Q
Who gets Hep B?
A
Blood-blood transfusion
Sex
Mother-child : effectively prevented by immunization of baby at birth
PWIDs
2
Q
How does Hep B present?
A
Acute presentation:
- Can be asymptomatic
- Similiar to hep A but more severe
3
Q
How is Hep B diagnosed?
A
- Hepatitis B surface antigen (HbsAg) present in blood of all infectious individuals
- Hep B e antigen (HbeAg) (active)
- Hep B virus DNA always present
- Hep B DNA
- Hep B IgM (Recent infections)
4
Q
How long must HBsAG be present in the blood to make a chronic infection?
A
6 months
5
Q
How is Hep B treated?
A
- Prevention through minimizing exposure
- Vaccination can prevent contraction
- Post-exposure vaccination + HBIG (hyperimmune hep B immunoglobin)
6
Q
How is chronic Hep B treatment?
A
Only treat when ALT and high HBV DNA
Entecavir, tenofovir: suppressive antiviral drugs (although only suppression)
7
Q
What could be a possible sustained cure?
A
Peginterferon
8
Q
High risk populations to get it are?
A
Men who have sex with men
IVDU
Those born in africa or indian sub-continent
9
Q
What type of virus is hep B?
A
DNA virus
