Small Vessel Vasculitis

Question 1

What is granulomatous is wit polyangitis?

Answer 1

AKA Wegener’s granulomatous is Wegner’s disease It is the most common cause of proteinase 3-mediated ANCA damage, generating oxygen free radicals affects vasculitis.

Question 2

Which systems are affected in granulomatous is with polyangitis?

Answer 2

Causes granuloma in respiratory tract and kidneys with necrotising glomerulonephritis due to ischaemia, causing an increase in BP. Involves the kidneys, nasopharyngeal

Question 3

How does granulomatous is with polyangitis present?

Answer 3

Saddle nose deformity due to inflammation of vessels causing erosion of cartilage and bone
Recurrent sinusitis
Haemoptysis
Rapidly progressive glomerulonephritis

Question 4

Which finding on blood test is used to confirm diagnosis?

Answer 4

C-ANCA

Question 7

What is Henoch-Schonlein purpura?

Answer 7

Henoch-Schönlein Purpura is characterised by palpable purpura, renal involvement, and can present with hypertension and haematuria

Question 8

What does Peri-nuclear anti-neutrophil cytoplasmic antibodies indicate?

Answer 8

Churn-Struass

Question 9

What does cytoplasmic anti-neutrophil cytoplasmic antibodies indicate?

Answer 9

Granulomatous is with polyangitis

Question 10

Which drug can cause Henoch-Schnonlein purpura?

Answer 10

Anastrozole, An aromatase enzyme inhibior

Question 11

When does Henoch-schnolein purrs commonly occur?

Answer 11

In children following infection

Question 12

What should e monitored in HSPP?

Answer 12

Blood pressure and urinalysis for renal involvement