Nephritic Syndrome Flashcards
What are the key features of nephritic syndrome?
haematuria, proteinuria (usually non-nephrotic range i.e. < 3.5 grams/day), hypertension, oliguria and oedema.
What conditions are associated with with nephiritc?
Alport syndrome
IgA nephoropathy
Malaria
Membranouproliferative
Hepatitis B
Post-streptococcal
Henoch-schonlien purpura
What does classic nephritic presentation with alopeica and rashes indicate?
Systemic lupus
What does classic nephritic presentation with haemoptysis and dyspnoea?
Anti-glomerular basement membrane disease
What does classic nephritic presentation with purpuric rash, arthritis and abdominal pain indicate?
Henoch-schonlein purpura
When is p=ANCA raised?
Eosniophilic granulomatous is with polyangitis
Microscopic polyangitis
When is C-ANCA raised?
Granulomatous is with polyangitis
What is the serology for post-infectious glomerulonephritis?
Antistreptolysin titre
HIV
Hepatitis B and C
What is the cause of starry sky biopsy appearance?
Post-streptococcal glomerulonephritis due to IgG and subepithelial deposits
What are causes of rapidly progressive glomerulonephritis?
Goodpasture;’s disease
Granulomatous is with polyangitis is
Lupus
What is the prognosis of IgA nephropathy?
Isolated microscopic haematuria with resolution of renal impairment
What are the poor prognostic factors for IgA nephropathy?
Hypertension
Older age
Presence of proteinuria and renal impairment
-> these factors make 15-30% progress to end stage renal disease
What is streptococcus pyogenes associated with with?
Scarlett fever
