Passmed GI

Question 1

What are aminosalicylates associated with?

Answer 1

Agranulocytosis

Question 3

What is biliary atresia?

Answer 3

Paediatric condition causing obliteration of the extrahepatic biliary system causing bile obstruction

Question 4

What is biliary atresia affected?

Answer 4

More common in females
Typically affects neonatal children

Question 5

What is type 1 biliary atresia?

Answer 5

Type 1: The proximal ducts are patent, however, the common duct is obliterated

Question 6

What is type 2 biliary atresia?

Answer 6

Type 2: There is atresia of the cystic duct and cystic structures are found in the porta hepatis

Question 7

What is type 3 biliary atresia?

Answer 7

Type 3: There is atresia of the left and right ducts to the level of the porta hepatis, this occurs in >90% of cases of biliary atresia MOST COMMON

Question 8

How does biliary atresia present?

Answer 8

Jaundice
Dark urine and pale stools
Appetite and growth disturbance

Question 9

What are the signs of biliary atresia?

Answer 9

Jaundice
Hepatomegaly with splenomegaly
Abnormal growth
Cardiac murmurs

Question 10

What are key features of bleary atresia on investigation?

Answer 10

Conjugated hyperbilirubinaemia

Question 11

What is the management of biliary atresia?

Answer 11

Surgical intervention
Antibiotic coverage
Bile acid enahncers

Question 12

What is the complications of biliary atresia?

Answer 12

Progressive liver disease
Cirrhosis with hepatocellular carcinoma
Unsuccessful anastomosis