Liver Biopsy And Tests Flashcards
What is a marker of liver function?
PT time
-> albumin has a half life of 2 weeks
When is ALT higher than ALT?
Alcohol related liver disease like alcoholic hepatitis
Advanced fibrosis in NAFLD or hepatitis C
What causes elevated serum IgA?
Alcohol related liver disease
NAFLD
What is the profile for alcohol liver disease?
High ALT to AST
High GGT
ALP will be normal
What is used to diagnose EBV?
Mono spot test
Paul-Bunnell test
What is the non invasive liver screen?
Testing for Hepatitis B and C and E antibiotic is
HIV testing
Autoimmune profile
Getting
Copper and ceruloplasmin
Alpha 1 antitrypsin
Coeliac serology
What does the autoimmune proliferation include?
Antismooth muscle antibody
Anti-liver-kidney-mitochondria
Anti-mitochondrial antibody
What does Anti-mitochondrial antibody indicate?
Primary biliary cholangitis
Which drug commonly causes jaundice?
Co-amoxicillin with mixed hepatitis and cholestasis picture and a 4 week delay in symptoms
Which drugs cause exclusively hepatitis?
Alcohol
Paracetomol
Statins
Anti-tuberculosis drugs
UTI drug nitrofurantoin
Amiodarone
Which drugs caused mixed cholestasis and hepatitis?
Oral contraceptive pill
Anabolic steroids and testosterone
Fibrates
Antibiotics like co-amoxiclav/eryhtormycin/azithromycin
Sulphonylurea urea
Which drugs can cause liver cirrhosis?
Methotrexate
Methyldopa
Amiodarone
What is the MELD score?
Model for end stage liver disease, which estimates a patient’s likelihood of surviving a liver transplant.
What are the features of the MELD score?
INR
Creatinine
Bilirubin
Sodium
