Hypothyroidism Flashcards
What is a sign specific to hypothyroidism?
Hertoghe sign which is loss of the lateral eyebrow
Other signs include hoarse voice
What is used to treat my Dena coma?
Hashimoto’s, diffuse painless goitre associated with Anti-TPO & Anti-Tg and HLA-DR3.
What is the most common cauase of hypothyroidism worldwide?
Iodine insufficiency
What is the TFT for overt primary hyperthyroidism?
Overt primaryhypothyroidismis characterised byhighTSH levels and low T4 levels
What is the TFT for subclinical hypothyoridism?
High TSH, normal T3 and T4
In order todiagnosesubclinical hypothyroidism, perform repeatTFTs3 months after the initial result
What is the TFT for secondary hypothyoridism?
Inappropriately low/normal TSH and, low free T4
What can interfere with levothyroxine?
Iron supplements canreducethe absorption oflevothyroxineand so they should be given2 hours apart
Which infiltrative disorders can cause hypothyroidism?
Haemochromatosis
Sarcoidosis
What are the neurological features of hypothyoridism?
Carpal tunnel syndrome
Slow reflexes
Peripheral neuropathy
How is hypothyroidism managed during pregnancy?
Dose of levothyroxine is increased due to metabolic demand increase
What is used to treat myxdema coma?
Liothyronine, active T3
Which drug can cause hypothyroidism?
Lithium
