Sarcoidosis Flashcards
What are the dermatological manifestations of sarcoidosis?
Erythema nodosum (inflammation of subcutaneous fat leading to tender nodules especially on the shins)
Lupus pernio (red/purple plaques and nodules on the face)
Hyper or hypopigmentation of the skin
What are the neurological manifestations?
Meningitis
Peripheral neuropathy
Facial nerve palsy
What are the ocular manifestations?
Uveitis
Glaucoma
What are the cardiac manifestations?
Restrictive cardiomyopathy
Syncope
What is Lofgren’s syndrome?
Fever
Polyarthralgia
Erythema nodosum
Bilateral hilar lymphadenopathy
What is Heerfordt’s syndrome?
Fever
Uveitis
Parotid swelling
Facial nerve palsy
What are the diagnostics on the FBC?
High ACE and calcium
What is the diagnostic imaging?
High resolution CT
What is god standard diagnosis?
Biopsy for noncaseating granuloma
What will bronchoalveolar lavage show?
Sudden cardiac death
Aspergillomas in the cavities
Pulmonary hypertension
What is first line treatment?
Prednisolone
What is second line treatment?
Immunosuppressant
What is third line treatment?
Biologic therapy like infliximab
What ae the complications fo sarcoidosis?
Sudden cardiac death
Aspergillomas in the cavities
Pulmonary hyperteniosn
What is lupus pernio?
Purplish raised rash
