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Step 1 Review > Resp Pharm High Yield > Flashcards

Resp Pharm High Yield Flashcards

1
Q

Name the class:

Loratadine
Fexofenadine
Desloratidine
Cetirizine

A

2nd generation H1 blocker

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2
Q

Name the class:

Diphenhydramine
Dimenhydrinate
Chlorphehydramine

A

1st generation H1 blockers

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3
Q

What are the H1 blockers used for?

A

Allergies

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4
Q

What is Gauifenesin?

A

Expectorant–> thins respiratory secretions

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5
Q

What is NAC?

A

Mucolytic (loosens mucus plugs in a paint with CF bu disrupting disulfide bonds)

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6
Q

What is dextromethorphan?

A

Antitussive (antagonizes NMDA glutamate receptors–> codeine analog)

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7
Q

What is the mechanism of pseudoephedrine and phenylephrine?

A

Alpha adrenergic agonists (as a nasal degongestant)

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8
Q

What is bosentan?

A

Endothelin receptor antagonist used to treat pulmonary HTN

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9
Q

What is the AE of bosentan?

A

Hepatotoxic

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10
Q

What are PDE-5 inhibitors used to treat?

A

ED

Pulm HTN

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11
Q

What 2 factors cause bronchosconstriction in asthma?

A

1- inflammatory process

2- Parasympathetic tone

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12
Q

Which beta 2 agonist is used for acute attacks?

A

albuterol

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13
Q

Which beta 2 antagonist is used for prophylaxis?

A

Salmeterol/ formoterol

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14
Q

What is 1st line therapy for chronic asthma?

A

Corticosteroids

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15
Q

What is the mechanism of ipratropium?

A

M blocker–> prevent bronchoconstriction

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16
Q

What is ipratropium used to treat?

A

COPD and asthma

17
Q

Which drug is an inhibitor of 5- lipoygenase pathway?

A

Zileutron

18
Q

What drugs block leukotriene receptors?

A

Montelukast

Zafirlukast

19
Q

What is omalizumab?

A

monoclonal anti-IgE antibody

20
Q

What is the mechanism of theophylline?

A

Causes bronchodilation by inhibiting phosphodiesterase leading to increased cAMP

21
Q

What are the AE of theophylline?

A

Cardiotoxicity, neurotoxicity

22
Q

What is used in aspirin induced asthma?

A

Montelukast, zafirlukast

23
Q

What is used in allergic asthma resistant to inhaled steroids and long acting Beta 2 agonists?

A

Omalizumab

Step 1 Review (62 decks)

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