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Step 1 Review > Cytokines High Yield > Flashcards

Cytokines High Yield Flashcards

1
Q

What cytokine activates osteoclasts?

A

IL-1

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2
Q

What cytokine causes fever and acute inflammation?

A

IL-1

IL-6

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3
Q

What cytokine induces expression of acute phase reactants?

A

IL-6

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4
Q

What cytokine is a major chemotactic factor for neutrophils?

A

IL-8

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5
Q

What cytokine leads to differentation of T cells into Ih1 cells?

A

IL-12

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6
Q

What cytokine activates NK cells?

A

IL-12

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7
Q

What cytokine mediates septic shock?

A

TNF- alpha

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8
Q

What cytokine stimulates all types of T cells?

A

IL-2

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9
Q

What cytokine stimulates bone marrow stem cells (growth and proliferation)?

A

IL-3

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10
Q

WHat cytokine stimulates macrophages?

A

IFN- gamma

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11
Q

What cytokine stimulates IgE production?

A

IL-4

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12
Q

What cytokine induces differentiation into Th2 cells?

A

IL-4

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13
Q

What cytokine stimulates IgA production?

A

IL-5

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14
Q

What cytokine promotes differention of B cells?

A

IL-5

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15
Q

What cytokine promotes the GROWTH of B cells?

A

IL-4

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16
Q

Which cytokine decreases expression of MHC II and Th1 cytokines?

A

IL-10

17
Q

Which cytokine inhibts activated macrophages and dendritis cells?

A

IL-10

18
Q

What cells secrete IL-10?

A

Th2 cells and T regs

19
Q

What cells secrete IL-1?

A

Macrophages

20
Q

What cells secrete IL-2?

A

ALL T cells

21
Q

What cells secrete IFN gamma?

A

Th1 cells

22
Q

What cells secrete IL-6?

A

Macrophages

23
Q

What cells secrete IL-3?

A

ALL T cells

24
Q

What cells secrete IL-5?

A

Th2 cells

25
Q

What cells secrete IL-8?

A

Macrophages

26
Q

What cells secrete TNF- alpha?

A

Macrophages

27
Q

What cells secrete IL-12?

A

Macrophages

28
Q

Which cytokiness help protect against RNA and DNA viruses?

A

IFN alpha and IFN beta

29
Q

What are interferon alpha and beta?

A

Glycoproteins–> act locally to prime cells for viral defense by degrading viral nucleic acid and protein

Step 1 Review (62 decks)

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