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Step 1 Review > General Pharm High Yield > Flashcards

General Pharm High Yield Flashcards

1
Q

What is the antidote for beta blockers?

A

Glucagon

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2
Q

What is the antidote for copper/ arsenic or gold poisoning?

A

Penicillamine

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3
Q

What is the antidote for cyanide toxicity?

A

Nitrate + thiosulfate

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4
Q

What is the antidote for Fe poisoning?

A

Deferoxamine

Deferasirox

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5
Q

What is the treatment for Lead poisoning?

A

EDTA, dimercaprol succimer, penicillamine

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6
Q

What is the antidote for mercury/ arsenic/ gold?

A

Dimercaprol, BAL and succimer

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7
Q

What is the treatment for methanol or ethylene glycol toxicity?

A

Fomepizole

Enthanol

Dialysis

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8
Q

What is the antidote for methemoglobin?

A

Methyl blue, vitamin C

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9
Q

What is the treatment for salicylates (aspirin)?

A

NaHCO3

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10
Q

Name 4 drugs that can cause cutaenous flushing?

A

Vancomycin
Adenosine
Niacin
Ca channel blockers

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11
Q

Which drugs can cause dilated cardiomyopathy?

A

Doxorubicin and daunorubicin

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12
Q

How can drug induced dilated cardiomyopathy be prevented?

A

Dexrazoxane

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13
Q

What drugs can cause TdP?

A

Class III and IA antiarrhythmics
Macrolides
Antipsychotics
TCAs

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14
Q

What drugs can cause hyperglycemia?

A 
Tarolimus
Protease inhibitors
Niacin
HCTZ
Corticosteroids
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15
Q

What drugs cause hypothyroidism?

A

Lithium
Amiodarine
Sulfonamides

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16
Q

What drugs can cause focal to massice hepatic necrosis?

A

Halothane
Amanita phalloides
Valproic acid
Acetaminophen

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17
Q

What 5 drugs cause hepatitis?

A 
1- rifampin
2- Isoniazid
3- Pyrazinamide
4- Statins
5- Fibrates
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18
Q

What 6 drugs can cause pancreatitis?

A 
1- Didanosine
2- corticosteroids
3- alcohol
4- valproic acid
5- azathoprine
6- diuretics
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19
Q

Which 6drungs can cause agranulocytosis?

A 
Gancyclovir
Clozapine
Carbamazepine
Colchicine
Methimazole
Propylthiouracil
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20
Q

What 6 drugs can cause aplastic anemia?

A 
Carbemazepine
Methimazole
NSAIDs
Benzene
Chloramphenicol
Propylthiouricil
21
Q

Drugs that give a positive direct coombs test?

A

Methyldopa

Penicillin

22
Q

Which drugs cause hemolysis in G6PD deficiency?

A 
Isoniazid
Sulfonamides
Dapsone
Primaqine
Aspirin
Ibuprofen
Nitrofurantion
23
Q

What 3 drugs can cause megaloblastic anemia?

A

Phenytoin
Methotrexate
Sulfa drugs

24
Q

Which drugs can cause gingival hyperlasia?

A

Phenytoin
CCBs
yclosporine

25
Q

Which drugs can cause hyperuriciemia?

A 
Pyrazinamide
Thiazides
Furosemide
Niacin
Cyclosporine
26
Q

What drugs cause osteoporosis?

A

corticosteroids

heparin

27
Q

Which drugs cause photosensitivity?

A

Sulfonamides
Amiodarone
tetracyclines
5-FU

28
Q

Which drugs cause a stevens johnson syndrome?

A

Antiepileptic drugs
allopurinol
sulfa drugs
penicillin

29
Q

What 6 drugs can cause SLE like syndrome?

A 
Sulf drugs
Hydralazine
Isoniazid
Procainamide
Phenytoin
Etanercept
30
Q

Which drugs cause tendonitis?

A

Fluoroquinolones

31
Q

Which 4 drugs can cause seizures?

A

Isoniazid, bupropion, imipenem/ cilastatin, enflurane

32
Q

Which 3 drugs can cause interstitial nephritis?

A

Methicillin
NSAIDS
Furosemide

33
Q

Which 4 drugs can cause pulmonary fibrosis?

A

Bleomycin
Amiodarine
Busulfan
Methotrexate

34
Q

Which 5 drugs cause a disulfram like reaction?

A 
Metronidazole
Cephalosporins
Griseofulvin
Procarbazine
1st generation sulfonylureas
35
Q

P450 inducer or inhibitor:

cimetidine

A

inhibitor

36
Q

P450 inducer or inhibitor:

Griseofulvin

A

inducer

37
Q

P450 inducer or inhibitor:

sulfonamides

A

inhibitor

38
Q

P450 inducer or inhibitor:

St. John’s Wart

A

inducer

39
Q

P450 inducer or inhibitor:

Phenytoin

A

inducer

40
Q

P450 inducer or inhibitor:

carbemazepine

A

inducer

41
Q

P450 inducer or inhibitor:

Ketokonazole

A

inhibitor

42
Q

P450 inducer or inhibitor:

Amiodarone

A

inhibitor

43
Q

P450 inducer or inhibitor:

isoniazid

A

inhibitor

44
Q

P450 inducer or inhibitor:

phenobarbitol

A

inducer

45
Q

P450 inducer or inhibitor:

ritonavir

A

inhibitor

46
Q

P450 inducer or inhibitor:

Macrolides

A

inhibitor

47
Q

P450 inducer or inhibitor:

chronic alcohol use

A

inducer

48
Q

P450 inducer or inhibitor:

quinidine

A

inhibitors

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