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General Pharm High Yield Flashcards

1
Q

What is the antidote for beta blockers?

A

Glucagon

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2
Q

What is the antidote for copper/ arsenic or gold poisoning?

A

Penicillamine

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3
Q

What is the antidote for cyanide toxicity?

A

Nitrate + thiosulfate

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4
Q

What is the antidote for Fe poisoning?

A

Deferoxamine

Deferasirox

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5
Q

What is the treatment for Lead poisoning?

A

EDTA, dimercaprol succimer, penicillamine

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6
Q

What is the antidote for mercury/ arsenic/ gold?

A

Dimercaprol, BAL and succimer

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7
Q

What is the treatment for methanol or ethylene glycol toxicity?

A

Fomepizole

Enthanol

Dialysis

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8
Q

What is the antidote for methemoglobin?

A

Methyl blue, vitamin C

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9
Q

What is the treatment for salicylates (aspirin)?

A

NaHCO3

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10
Q

Name 4 drugs that can cause cutaenous flushing?

A

Vancomycin
Adenosine
Niacin
Ca channel blockers

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11
Q

Which drugs can cause dilated cardiomyopathy?

A

Doxorubicin and daunorubicin

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12
Q

How can drug induced dilated cardiomyopathy be prevented?

A

Dexrazoxane

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13
Q

What drugs can cause TdP?

A

Class III and IA antiarrhythmics
Macrolides
Antipsychotics
TCAs

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14
Q

What drugs can cause hyperglycemia?

A 
Tarolimus
Protease inhibitors
Niacin
HCTZ
Corticosteroids
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15
Q

What drugs cause hypothyroidism?

A

Lithium
Amiodarine
Sulfonamides

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16
Q

What drugs can cause focal to massice hepatic necrosis?

A

Halothane
Amanita phalloides
Valproic acid
Acetaminophen

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17
Q

What 5 drugs cause hepatitis?

A 
1- rifampin
2- Isoniazid
3- Pyrazinamide
4- Statins
5- Fibrates
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18
Q

What 6 drugs can cause pancreatitis?

A 
1- Didanosine
2- corticosteroids
3- alcohol
4- valproic acid
5- azathoprine
6- diuretics
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19
Q

Which 6drungs can cause agranulocytosis?

A 
Gancyclovir
Clozapine
Carbamazepine
Colchicine
Methimazole
Propylthiouracil
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20
Q

What 6 drugs can cause aplastic anemia?

A 
Carbemazepine
Methimazole
NSAIDs
Benzene
Chloramphenicol
Propylthiouricil
21
Q

Drugs that give a positive direct coombs test?

A

Methyldopa

Penicillin

22
Q

Which drugs cause hemolysis in G6PD deficiency?

A 
Isoniazid
Sulfonamides
Dapsone
Primaqine
Aspirin
Ibuprofen
Nitrofurantion
23
Q

What 3 drugs can cause megaloblastic anemia?

A

Phenytoin
Methotrexate
Sulfa drugs

24
Q

Which drugs can cause gingival hyperlasia?

A

Phenytoin
CCBs
yclosporine

25
Which drugs can cause hyperuriciemia?
``` Pyrazinamide Thiazides Furosemide Niacin Cyclosporine ```
26
What drugs cause osteoporosis?
corticosteroids | heparin
27
Which drugs cause photosensitivity?
Sulfonamides Amiodarone tetracyclines 5-FU
28
Which drugs cause a stevens johnson syndrome?
Antiepileptic drugs allopurinol sulfa drugs penicillin
29
What 6 drugs can cause SLE like syndrome?
``` Sulf drugs Hydralazine Isoniazid Procainamide Phenytoin Etanercept ```
30
Which drugs cause tendonitis?
Fluoroquinolones
31
Which 4 drugs can cause seizures?
Isoniazid, bupropion, imipenem/ cilastatin, enflurane
32
Which 3 drugs can cause interstitial nephritis?
Methicillin NSAIDS Furosemide
33
Which 4 drugs can cause pulmonary fibrosis?
Bleomycin Amiodarine Busulfan Methotrexate
34
Which 5 drugs cause a disulfram like reaction?
``` Metronidazole Cephalosporins Griseofulvin Procarbazine 1st generation sulfonylureas ```
35
P450 inducer or inhibitor: cimetidine
inhibitor
36
P450 inducer or inhibitor: Griseofulvin
inducer
37
P450 inducer or inhibitor: sulfonamides
inhibitor
38
P450 inducer or inhibitor: St. John's Wart
inducer
39
P450 inducer or inhibitor: Phenytoin
inducer
40
P450 inducer or inhibitor: carbemazepine
inducer
41
P450 inducer or inhibitor: Ketokonazole
inhibitor
42
P450 inducer or inhibitor: Amiodarone
inhibitor
43
P450 inducer or inhibitor: isoniazid
inhibitor
44
P450 inducer or inhibitor: phenobarbitol
inducer
45
P450 inducer or inhibitor: ritonavir
inhibitor
46
P450 inducer or inhibitor: Macrolides
inhibitor
47
P450 inducer or inhibitor: chronic alcohol use
inducer
48
P450 inducer or inhibitor: quinidine
inhibitors

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