High Yield from Questions Flashcards

1
Q

What mutation causes chronic granulomatous disease?

A

inactivating mutation affecting NADPH oxidase–> inhibits phagocytic intracellular killing

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2
Q

What types of organisms generate recurrent infections in people with chronic granulomatous disease?

A

catalase positive

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3
Q

Mucicarmine stain can help to identify which fungi?

A

Cryptococcus neoformans (polysaccharide capsule)

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4
Q

What bacteria cause intracellular infections? (8)

A

Chlamydia, legionella, Listeria, Mycobacterium, Neisseria meningitidis, Nocardia, Rickettsia, Salmonella typhi

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5
Q

What is the primary immune mechanism against intracellular infections?

A

Cell mediated immunity

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6
Q

Which Cephalosporins can treat pseudomonas?

A

Ceftazidime and defepine (3rd and 4th generation)

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7
Q

Which cephalosporin is used to treat community aquired pneumonia?

A

Ceftriaxone

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