Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Step 1 Review > GI Pharm High Yield > Flashcards

GI Pharm High Yield Flashcards

1
Q

Name the class:

Cimetidine
Ranitidine
Famotidine

A

H2 Blocler

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Does cimetidine induce or inhibit P450?

A

Inhibit!!!!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

AE of H2 blockers?

A

antiandrogenic effects, cross BBB to cause confusion/ dizzy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which H2 blockers should not be used in renal dysfunction?

A

Cimitidine and ranitidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Name the class:

Omeprazone
lansoprzole
esomeprazole

A

PPI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Are PPI’s reversible or irreversible?

A

irreversible

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

AE of PPI’s?

A

C. diff, pneumonia, decrease serum Mg2+

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Mechanism of bismuth sucralfate?

A

bind to ulcer base and provide protection

allow HCO3 secretion to reestablish pH gradient in the mucous layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

PGE1 analog?

A

misoprostol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Who is misoprostol contraindicated in?

A

women of childbearing potential (antiabortive)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Mechanism of octreotide?

A

long acting somatostatin analog

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What metabolic imbalance can ALL antacids cause?

A

hypokalemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Name the class:

Magnesium hydroxide
Magnesium citrate
Polyethylene glycol
Lactulose

A

Osmotic laxatives

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Name the class:

Aluminum hydroxide
calcium carbonate
Magnesium hydroxide

A

Antacids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

AE of calcium carbonate?

A

Hypercalcemia and rebound acid increase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Dx used to treat hepatic encephalopathy?

A

Lactulose–> promotes the excretion of NH4+

17
Q

What is Sulfasalazine?

A

combo of sulfapyridine (antibacterial) and 5- aminosalicylic acid (anti inflammatory)

18
Q

What is sulfasalazine used for?

A

UC, CD

19
Q

Mechanism of ondansetron?

A

5HT3 antagonist–> decrease vagal stimulation–> anti-emetic properties

20
Q

AE of ondansetron?

A

HA, constipation, QT interval prolongation

21
Q

Name the mechanism?

Metoclopramde

A

D2 receptor antagonist–> increase resting tone of LES and promote motility

22
Q

AE of metoclopramide?

A

TD, parkinson effects

Step 1 Review (62 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions