muscle contractions 2 Flashcards

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1
Q

What is a network of internal membranes that runs through the sarcoplasm called

A

The sarcoplasmic reticulum

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2
Q

What does the sarcoplasmic reticulum do

A

The sarco plasmic reticulum stores and rele ases calcium ions that are needed for muscle contraction

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3
Q

What do muscle fibres contain alot of

A

M uscle fibres have lots of mit ocho ndria to provide

the ATP that’s needed for muscle contraction.

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4
Q

What is multinucleate

A

M uscle fibres are multinuclea te (contain many nucle i).

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5
Q

What are myofibrils

A

M uscle fibres have lots of long, cylin drical organelles c alle d myofibrils. They’re made up of proteins and are highly sp ecialised for co ntraction.

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6
Q

What do myofibrils contain

A

Myofibrils Contain Thick Myosin Filaments and Thin Actin myofilaments hat move past each other to make muscles co ntract

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7
Q

What are thick myofuilaments are made of

A

Thick myofilaments are made of the protein myosin.

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8
Q

What are thin filaments made of

A

Thin myofilaments are made of the protein actin

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9
Q

If you look at a myofibril under an electron microscope what will you see

A

If you look at a myofibril under an electron microsco pe, yo u’ll see a pattern of alternating dark and light bands:

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10
Q

When looking at myofibril under an electron microscope what are the dark bands mad eof

A

Dark bands contain the thick myosin filaments and some overlapping thin actin filaments — these are calle d A-band

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11
Q

f you look at myofibril under a microscope what are the light bands made of

A

Light bands contain thin actin filaments o nly — these are calle d I-bands

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12
Q

What is a myofibril made up of

A

A myofibril is made up of many short units calle d sarcomeres., A myofibril is made up of many short units calle d sarcomeres.

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13
Q

What is the sliding filament theory

A

The theory explaining muscle contraction,
Myosin and actin filaments slide over one another to make the sarcomeres contract — the myofilaments themselves don’t contract. the myofilaments themselves don’t contract. The simultaneous contractio n of lots of sarcomeres means the myofibrils and muscle fibres contract. Sarcomeres return to their original length as the muscle relaxes.

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14
Q

What do myosin filaments contain

A

Myosin filaments have glo bular heads that are hinged, so they can move backand forth. 2) Each myosin head has a binding site for actin and a binding sit e for ATP.

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15
Q

What do actin filaments contain

A

Actin filaments have binding sites for myosin heads, calle d actin-myosin binding sites

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16
Q

What is tropomyosin and what does it do

A

Another protein calle d tropomyosin is found between actin filaments. It helps myofilaments move past each other.

17
Q

What does tropomyosin block

A

Binding Sites in Resting Muscles are Blocked by Tropomyosin. ) So myofilaments can’t slide past each other because the myosin heads
can’t bind to the actin-myosin binding site on the actin filaments.

18
Q

What is muscle contraction triggered by

A

Influx of calcium ions

19
Q

What happens when an action potential from a motor neurone stimulates a muscle cell

A

it depolarises the sarcolem ma. Dep olarisation spreads down the T-tubules to the sarco plasmic reticulumThis causcs the sarco plasmic reticulum to release stored ca lciu m ions (Ca2+) into the sarcoplasm.

20
Q

What do calcium ions bind to

A

Ca lcium ions bind to a protein attached to C a * binds to a protein, which moves tropomyosin myosin he a d_ binds to the exposed site actin-myosin cross bridge formed tropomyosin, causing the protein to change shape. This p ulls the attached tropomyosin out of the actin-myosin binding site on the actin filament. This ex poses the binding site, which allows the myosin head to bind

21
Q

What is an actin myosin cross bridge

A

The bond formed when a myosin head binds to an actin filamen t

22
Q

What do calcium ions also activate

A

Calcium ions also activat e the enzym e ATP hydrolase which hydrolyses (breaks d own) ATP (into A D P + P;) to provide the energy needed for muscle contraction.

23
Q

What does the energy released from ATP cause

A

The energy released from ATP causes the myosin head to bend, which pulls the actin filament along in a kind of rowing action.

24
Q

How does the myosin head detach from the filament after its moved

A

Another A TP m ole cule provides the energy to break the actin-myosin cross bridge, so the myosin head de taches from the actin filament after it’s moved.

25
Q

What does teh myosin head reattach to after detaching from the actin filament

A

The myosin head then rea ttaches to a different binding site further along the actin filament. A new actin-myosin cross bridge is formed and the cycle is repea ted (attach, move, detach, reattach to new bin din g site

26
Q

What exactly causes the muscle to contract

A

Many cross bridges form and break very rapidly, pulling the actin filament along — which shortens the sarcomere, causing the muscle to contract 11) The c yc le will co ntinue as long as calciu m ions are present.