Blood Water Potential Control Flashcards
Ultra filtration
In glomerulus and bowman’s capsule
Ultra filtration is filtration under high hydrostatic pressure created in the glomerulus due to a difference in diameter of the arterioles: afferent wider than efferent arteriolar so high blood pressure in the renal artery greater than water potential of blood
Capillary endothelial cell has walls
Pores in basement membrane forms a filter between the blood and the nephron
Podocytes create filtration slots on epithelial layer of the capsule
Acts as a molecular sieve :blood cells and large proteins stay in the blood as they are too large
Much of the blood plasma (including dissolved small glucose and urea) passes through into the bowman’s capsule as filtrate
How is proximal convoluted tube adapted to reabsorption
Large surface area many micro Villi
Lots of mitochondria to synthesise arp for active transport
Close to blood capillaries
How does loop of Henley provide osmotic gradient in the medulla for reabsorption of water
Loop of henle creates a high concentration of salts with a low water potential in the medulla for reabsorption of water by osmosis from descending limb and collecting duct by osmosis, reducing the volume of the filtrate
Ascending limb is impermeable to water and cells actively transport na+ into the tissue fluid of the medulla
Descending limb cells are permeable to water so water moves out of the filtrate by osmosis down water potential gradient
Adaptations of loop of henle
The loop of henle reduces the water potential of the medulla by losing ions at the bottom of the loop and by active transport
A longer loop would lose more ions and create a lower water potential in the medulla than other organisms
A shorter loop would lose less ions and create a higher water potential in the medulla than other organisms
How is sodium ion gradient maintained in the loop of henle
Mitochondria in the walls of the cells provide energy to actively transport sodium ions out of the ascending limb of the loop of henle
The accumulation of sodium ions in outside of the nephron in the medulla lowers the water potential
Therefore water diffuses out by osmosis into the interstitial space and then the blood capillaries water is then reabsorbed into the blood
At the base of the ascending limb some sodium ions are transported about by diffusion as there is now a very dilute solution due to all the water that has moved out