Enzymes Flashcards

1
Q

What does the substrate do if the active site had a complimentary shape

A

It binds to the active site

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2
Q

What does the induced fit model say

A

The active site changes shape as it binds to the substrate

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3
Q

What is it called if the active site changes shape as it binds to the substrate

A

An enzyme substrate complex

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4
Q

What happens if the bond bends

A

It lowers the activation energy

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5
Q

What are the factors affecting the rate of a reaction

A

Substrate and enzyme concentration

Temperature

Oh

Inhibitors

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6
Q

What can increasing the concentration do

A

Increasing the concentration (adding kre enzyme and substrate) can increase the rate of ES complexes formed

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7
Q

What happens when you increase the temperature in a reaction

A

The particles move faster which increases the rate of enzyme substrates formed

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8
Q

What does high temp and pH change do to a reaction

A

If the active site changes shape (denatured) this will decrease the rate of ES complexes formed

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9
Q

What happens if the active site changes shape

A

It is called denatured

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10
Q

What happens to enzymes at low temperatures

A

They are inactives

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11
Q

What happens to enzymes at high temperatures

A

They denature

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12
Q

What does increasing the temperature too much do to the rate of reaction

A

It decreases the rate of reaction as hydrogen bonds are broken and the active site is not complimentary so fewer ES complexes are formed

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13
Q

What is denaturation

A

When a structure can be irreversibly altered by conditions

Active site changes shape- substrate can no longer bind

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14
Q

What happens if the pH changes in a reaction

A

The ionic bonds within the enzyme will change and fewer ES complexes will form

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15
Q

What is an inhibitor

A

A compound or macromolecule that blocks the action of an enzyme

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16
Q

What is a competitive inhibitor

A

Similar shape to the substrate

Binds to the active site

Fewer ES complexes formed

Increasing substrate concentration will increase the rate of reaction

17
Q

What is a non competitive inhibitor

A

Binds to a different site on enzyme

Denatured the active site (not complimentary)