Enzymes In Detail Flashcards
How do the enzymes lower the activation energy
Bending the bonds in substrate putting strain on the bonds,and making them more likely to break
Bringing molecules closer together,overcoming the natural repulsion between the two molecules,making a bond between the two molecules more likely
What are all the factors that can affect enzyme activity
Temperature,pH ,substrate or enzyme concentration
How can temperature effect enzymes
As temperature increases the kinetic energy of the enzyme and substrate increases and substrate increases,they are more likely to collide and form enzyme substrate complexes which increases the rate of reaction
What happens to an enzyme if it is above optimum temperature
Above the optimum temperature the hydrogen bonds in the tertiary structure break,the active site changes shape and is no longer complementary
Meaning enzyme substrate complexes can’t be formed and rate of reaction decreases
How does pH affect enzyme activity
Deviation away from the optimum pH changes causes changes in the ionic bonds between R groups the active site changes shape and is no longer complementary to the substrate. Enzyme substrate complexes cannot form and the rate of reaction decreases
How can substrate or enzyme concentration effect enzyme activity
As the concentration increases the rate of reaction increases
This is due to more collisions and an increase in enzyme-substrate complexes formed.
At high concentrations the rate levels off