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Clinical Pathology > Microbiology 2 (virology) > Flashcards

Microbiology 2 (virology) Flashcards

1
Q

Non enveloped DNA viruses

A

Parvovirus
Adenovirus
Papopvavirus (papilloma, polyoma)

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2
Q

enveloped DNA viruses

A

Herpes
Pox
Hepadna (HepB)

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3
Q

Non-enveloped RNA viruses

A

Calici (Norovirus)
Picorna (Enterovirus)
Reo (Rotavirus)

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4
Q

Enveloped RNA virus

A

everything else

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5
Q

Viruses with nuclear and cytoplasmic inclusions

A

CMV

Measles

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6
Q

Warthin-FInkeldy giant cells

A

measles

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7
Q

nuclear inclusions and syncytia formation

A

HSV (Cowdry bodies)

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8
Q

forms syncytia with no inclusions

A

RSV

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9
Q

CPE that “sweeps across” culture in 2-3 days

A

HSV 1 or 2

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10
Q

Ramsay-Hunt syndrome

A

reactivation of latent VZV from genticulate ganglion of facial nerve
otalgia, facial paresis, vertigo, hearing loss, tinnitus

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11
Q

human herpes viruses

A

HSV1&2, CMV, VZV, EBV, HHV-6, HHV-8

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12
Q

EBV infects ____ via_____

A

B-lymphocytes via the CD3 receptor (CD21)

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13
Q

Duncan disease clinical

A

X-linked lymphoproliferative disorder

fulminant primary EBV infection; hemophagocytosis, hepatic necrosis (T/NK cell infiltrate)

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14
Q

Duncan disease genetics

A

SH2D1A gene (also called SAP gene)

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15
Q

Hoagland criteria for infectious mono

A
  1. > 50% lymphs
  2. > 10% atypical lymphs
  3. fever
  4. pharyngitis
  5. adenopathy
    • serology
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16
Q

other causes of mononucleosis syndrome

A

Toxo, CMV, dilantin

17
Q

5 serologic EBV tests

A
  1. IgM Anti-VCA
  2. Heterophile
  3. IgG Anti-EA
  4. IgG Anti_VCA
  5. Anti-EBNA
18
Q

False + monospot

A

HIV, lupus, lymphoma

19
Q

Serology of remote EBV

A

IgG Anti-VCA+

Anti-EBNA +/-

20
Q

only EBV related lesions negative for EBER

A

oral hairy leukoplakia

21
Q

Syndroems caused by EBV (7)

A

Hodgkin, primary effusion lymphoma, lymphomatoid granulomatosis,PTLD, oral hairy leukoplakia, nasopharyngeal carcinoma

22
Q

HHV-6 causes

A

Roseola (exanthum subitum)

23
Q

HHV-8 causes

A

Kaposi, primary effusion lymphoma, muticentric castleman

24
Q

LANA-1 expression in specked nuclear pattern

25
Q

Adenovirus serotypes causing epidemic respiratory outbreaks

26
Q

adenovirus serotypes causing hemorrhagic cystitis

27
Q

Adenovirus serotypes causing diarrhea

28
Q

childhood parvovirus illness

A

erythema infectiosum (fifth dz)

29
Q

Polyomaviruses

30
Q

JC virus causes

A

progressive multifocal leukoencephalopathy

inclusions are in oligodeendroglioma cells

31
Q

BK virus causes

A

hemorrhagic cystitis

32
Q

Papovaviruses

A

polyomaviruses, papillomaviruses

33
Q

in benign lesions HPV DNA is ____;in malignant ones, it is____

A

episomal, integrated

34
Q

Bowenoid papulosis caused by ____

35
Q

non-enveloped RNA viruses tend to be

A

gastrointestinal

36
Q

Guarnerieri bodies

A

Variola (small pox)

37
Q

Category A bioterrorism agents

A 
Small pox
Anthrax
Plague
Botilism
Tularemia
Hemorrhagic fever

Clinical Pathology (59 decks)

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