Microbiology 2 (virology)

Question 1

Non enveloped DNA viruses

Answer 1

Parvovirus
Adenovirus
Papopvavirus (papilloma, polyoma)

Question 2

enveloped DNA viruses

Answer 2

Herpes
Pox
Hepadna (HepB)

Question 3

Non-enveloped RNA viruses

Answer 3

Calici (Norovirus)
Picorna (Enterovirus)
Reo (Rotavirus)

Question 4

Enveloped RNA virus

Answer 4

everything else

Question 5

Viruses with nuclear and cytoplasmic inclusions

Answer 5

CMV

Measles

Question 6

Warthin-FInkeldy giant cells

Answer 6

measles

Question 7

nuclear inclusions and syncytia formation

Answer 7

HSV (Cowdry bodies)

Question 8

forms syncytia with no inclusions

Answer 8

RSV

Question 9

CPE that “sweeps across” culture in 2-3 days

Answer 9

HSV 1 or 2

Question 10

Ramsay-Hunt syndrome

Answer 10

reactivation of latent VZV from genticulate ganglion of facial nerve
otalgia, facial paresis, vertigo, hearing loss, tinnitus

Question 11

human herpes viruses

Answer 11

HSV1&2, CMV, VZV, EBV, HHV-6, HHV-8

Question 12

EBV infects ____ via_____

Answer 12

B-lymphocytes via the CD3 receptor (CD21)

Question 13

Duncan disease clinical

Answer 13

X-linked lymphoproliferative disorder

fulminant primary EBV infection; hemophagocytosis, hepatic necrosis (T/NK cell infiltrate)

Question 14

Duncan disease genetics

Answer 14

SH2D1A gene (also called SAP gene)

Question 15

Hoagland criteria for infectious mono

Answer 15

1. > 50% lymphs
2. > 10% atypical lymphs
3. fever
4. pharyngitis
5. adenopathy
6. • serology

Question 16

other causes of mononucleosis syndrome

Answer 16

Toxo, CMV, dilantin

Question 17

5 serologic EBV tests

Answer 17

1. IgM Anti-VCA
2. Heterophile
3. IgG Anti-EA
4. IgG Anti_VCA
5. Anti-EBNA

Question 18

False + monospot

Answer 18

HIV, lupus, lymphoma

Question 19

Serology of remote EBV

Answer 19

IgG Anti-VCA+

Anti-EBNA +/-

Question 20

only EBV related lesions negative for EBER

Answer 20

oral hairy leukoplakia

Question 21

Syndroems caused by EBV (7)

Answer 21

Hodgkin, primary effusion lymphoma, lymphomatoid granulomatosis,PTLD, oral hairy leukoplakia, nasopharyngeal carcinoma

Question 22

HHV-6 causes

Answer 22

Roseola (exanthum subitum)

Question 23

HHV-8 causes

Answer 23

Kaposi, primary effusion lymphoma, muticentric castleman

Question 24

LANA-1 expression in specked nuclear pattern

Answer 24

HHV-8

Question 25

Adenovirus serotypes causing epidemic respiratory outbreaks

Answer 25

4+7

Question 26

adenovirus serotypes causing hemorrhagic cystitis

Answer 26

11,21

Question 27

Adenovirus serotypes causing diarrhea

Answer 27

40,41

Question 28

childhood parvovirus illness

Answer 28

erythema infectiosum (fifth dz)

Question 29

Polyomaviruses

Answer 29

JC and BK

Question 30

JC virus causes

Answer 30

progressive multifocal leukoencephalopathy

inclusions are in oligodeendroglioma cells

Question 31

BK virus causes

Answer 31

hemorrhagic cystitis

Question 32

Papovaviruses

Answer 32

polyomaviruses, papillomaviruses

Question 33

in benign lesions HPV DNA is ____;in malignant ones, it is____

Answer 33

episomal, integrated

Question 34

Bowenoid papulosis caused by ____

Answer 34

HPV 16

Question 35

non-enveloped RNA viruses tend to be

Answer 35

gastrointestinal

Question 36

Guarnerieri bodies

Answer 36

Variola (small pox)

Question 37

Category A bioterrorism agents

Answer 37

Small pox
Anthrax
Plague
Botilism
Tularemia
Hemorrhagic fever