Heme Path 2 Flashcards

1
Q

MPO stains

A

primary (azurophilic) granules of grans

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2
Q

sudan black stains

A

lipid in grans and monos

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3
Q

chloroacetate esterase

A

only stains grans

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4
Q

NSE

A

monocytes (inhibited by NaF)

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5
Q

PAS

A

“block” positivity in ALL

diffusely granular in AML

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6
Q

Pro-B phenotype

A
34
TdT
DR
19
10
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7
Q

Pre-B phenotype

A
DR
19
10
20
cytoplasmic mu
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8
Q

prothymocytes

A

34
TdT
2
7

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9
Q

thymocytes

A
TdT
1
2
c3
5
7
4+8
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10
Q

mature thymocytes

A

TdT neg
CD1 neg
4 or 8

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11
Q

nk cell markers

A

16 + 56

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12
Q

mono markers

A

CD11b, 15, 64, 14

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13
Q

t(2;5)

A

anaplastic large cell lymphoma

ALK +

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14
Q

Cyclin D1

A

(BCL-1)
Mantle cell lymphoma
Myeloma

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15
Q

germinal center markers

A

BCL6, CD10

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16
Q

CD1a + in

A

Langerhans cells
dendritic reticulum cells
interdigitating reticulum cells
cortical thymocytes

17
Q

normal CD4/CD8 ratio

A

2-6:1

18
Q

condition with increased circulating CD5+ B cells

A

RA

19
Q

Neoplasms with CD11c

A

CLL

Hairy cell

20
Q

other name for CD15

A

Leu-M1

21
Q

CD15 in anaplastic large cell lymphoma

A

negative

22
Q

AML with CD19 expression

A

classic for AML with t(8;21)

23
Q

CD25 is also

A

IL-2 receptor

24
Q

CD25+ in

A

Hairy cell

adult T-cell leukemia/lymphoma

25
Q

CD30 seen in (5)

A
plasma cells
RS cells
embryonal CA
anaplastic large cell lymphoma
mediastinal large B cell lymphoma
26
Q

CD38 signals aggressiveness of

A

CLL/SLL

27
Q

Mega markers

A

CD41, CD61

28
Q

CD43 expressed on B cells in (3)

A

Mantel cell lymphoma
CLL/SLL
marginal zone lymphoma

29
Q

CD45-RO seen on

A

T cellsq

30
Q

Sensitive and specific for Hairy cell

A

CD103