Heme Path 2 Flashcards
MPO stains
primary (azurophilic) granules of grans
sudan black stains
lipid in grans and monos
chloroacetate esterase
only stains grans
NSE
monocytes (inhibited by NaF)
PAS
“block” positivity in ALL
diffusely granular in AML
Pro-B phenotype
34 TdT DR 19 10
Pre-B phenotype
DR 19 10 20 cytoplasmic mu
prothymocytes
34
TdT
2
7
thymocytes
TdT 1 2 c3 5 7 4+8
mature thymocytes
TdT neg
CD1 neg
4 or 8
nk cell markers
16 + 56
mono markers
CD11b, 15, 64, 14
t(2;5)
anaplastic large cell lymphoma
ALK +
Cyclin D1
(BCL-1)
Mantle cell lymphoma
Myeloma
germinal center markers
BCL6, CD10
CD1a + in
Langerhans cells
dendritic reticulum cells
interdigitating reticulum cells
cortical thymocytes
normal CD4/CD8 ratio
2-6:1
condition with increased circulating CD5+ B cells
RA
Neoplasms with CD11c
CLL
Hairy cell
other name for CD15
Leu-M1
CD15 in anaplastic large cell lymphoma
negative
AML with CD19 expression
classic for AML with t(8;21)
CD25 is also
IL-2 receptor
CD25+ in
Hairy cell
adult T-cell leukemia/lymphoma
CD30 seen in (5)
plasma cells RS cells embryonal CA anaplastic large cell lymphoma mediastinal large B cell lymphoma
CD38 signals aggressiveness of
CLL/SLL
Mega markers
CD41, CD61
CD43 expressed on B cells in (3)
Mantel cell lymphoma
CLL/SLL
marginal zone lymphoma
CD45-RO seen on
T cellsq
Sensitive and specific for Hairy cell
CD103
