Hematology 3 Flashcards

1
Q

Plummer Vinson syndrome

A

Iron def anemia

Esophageal webs

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2
Q

Multicentric caslteman assd with what syndrome

A
POEMS
Polyneuropathy
organomegaly
endocrine changes
M-spike
skin changes
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3
Q

Heinz bodies seen in

A

G6PD def
pyruvate kinase def
unstable hemoglobin

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4
Q

EM finding in Hairy cel leukemia

A

Ribosome lamellar complex

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5
Q

Reactive neutrophilia without toxic changes

A

Hantavirus pulmonary syndrome

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6
Q

Hantavirus pulmonary syndrome (5)

A
  1. thrombocytopenia
  2. Left shift
  3. increased Hgb
  4. lack of toxic changes
  5. > 10% immunoblastic lymphs
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7
Q

syndrome of persistent polyclonal B lymphocytosis

A

young female smokers

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8
Q

Reider cell

A

assd with Pertussis
reactive lymphocytosis in children
clefted nuclei, very high WBC count

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9
Q

Infections associated with monocytosis

A

listeria, TB

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10
Q

Most common cuase of eosinophilia in the world

A

helminthic infection

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11
Q

Interleukin associated with eos

A

IL-5

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12
Q

Well syndrome

A

eosinophilic cellulitis

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13
Q

Loeffler syndrome

A

eosinophilic pneumonia

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14
Q

Shulmann syndrome

A

eosinophilic fasciitis

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15
Q

Churg-Strauss syndrome

A

eosinophilic vasculitis

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16
Q

Drugs causing neutropenia

A

antibiotics, anti-thyroid, anticonvulsants, procainamide, NSAIDs

17
Q

infections assd with neutropenia

A

typhoid, brucella, tularemia, rickettsia

18
Q

Felty syndrome

A
  1. RA
  2. splenomegaly
  3. neutropenia
19
Q

Cyclic neutropenia/congenital neutropenia

A

ELA2 related, assd with AML
compensatory monocytosis
arrest at promyelocyte stage
neutrophil elastase

20
Q

Congenital lymphopenia

A

Brutons, SCID, CVI, DiGeorge

21
Q

hereditary sideroblastic anemia

A

Pearson syndrome

22
Q

causes of acanthocytes (4)

A

McCloud phenotype, liver dz, abetalipoproteinemia, anorexia

23
Q

causes of ecchinocytes (3)

A

renal dz, EDTA artifact, pyruvate kinase deficiency

24
Q

hemoglobinopathy with target cells

A

HbC

25
Q

basophilic stippling

A

hemoglobinopathies, sideroblastic anemia, lead poisoning, porphyria, myelodysplasia, infection, pyrimadine 5’ nucleosidase deficiency