Hematology 3 Flashcards
Plummer Vinson syndrome
Iron def anemia
Esophageal webs
Multicentric caslteman assd with what syndrome
POEMS Polyneuropathy organomegaly endocrine changes M-spike skin changes
Heinz bodies seen in
G6PD def
pyruvate kinase def
unstable hemoglobin
EM finding in Hairy cel leukemia
Ribosome lamellar complex
Reactive neutrophilia without toxic changes
Hantavirus pulmonary syndrome
Hantavirus pulmonary syndrome (5)
- thrombocytopenia
- Left shift
- increased Hgb
- lack of toxic changes
- > 10% immunoblastic lymphs
syndrome of persistent polyclonal B lymphocytosis
young female smokers
Reider cell
assd with Pertussis
reactive lymphocytosis in children
clefted nuclei, very high WBC count
Infections associated with monocytosis
listeria, TB
Most common cuase of eosinophilia in the world
helminthic infection
Interleukin associated with eos
IL-5
Well syndrome
eosinophilic cellulitis
Loeffler syndrome
eosinophilic pneumonia
Shulmann syndrome
eosinophilic fasciitis
Churg-Strauss syndrome
eosinophilic vasculitis
Drugs causing neutropenia
antibiotics, anti-thyroid, anticonvulsants, procainamide, NSAIDs
infections assd with neutropenia
typhoid, brucella, tularemia, rickettsia
Felty syndrome
- RA
- splenomegaly
- neutropenia
Cyclic neutropenia/congenital neutropenia
ELA2 related, assd with AML
compensatory monocytosis
arrest at promyelocyte stage
neutrophil elastase
Congenital lymphopenia
Brutons, SCID, CVI, DiGeorge
hereditary sideroblastic anemia
Pearson syndrome
causes of acanthocytes (4)
McCloud phenotype, liver dz, abetalipoproteinemia, anorexia
causes of ecchinocytes (3)
renal dz, EDTA artifact, pyruvate kinase deficiency
hemoglobinopathy with target cells
HbC
basophilic stippling
hemoglobinopathies, sideroblastic anemia, lead poisoning, porphyria, myelodysplasia, infection, pyrimadine 5’ nucleosidase deficiency