Chemistry 15 (Endocrine)

Question 1

In hypothyroidism, T3 resin uptake is

Answer 1

low

Question 2

In hyperthyroidism, T3 resin uptake is

Answer 2

high

Question 3

rT3 increased in

Answer 3

euthyroid sick syndrome

Question 4

hyperthyroid pt with normal or low RAIU

Answer 4

struma ovarii or exogenous thyroid hormone

Question 5

TRH stimulation test in primary hypoparathyroidism

Answer 5

exaggerated TSH response to TRH

Question 6

most common cause of hypothyroidism

Answer 6

Hashimoto

Question 7

Refetoff syndrome

Answer 7

rare peripheral resistance to thyroid hormone

Question 8

Abs in hashimoto

Answer 8

anti-microsomal, anti-thyroglobulin

Question 9

genes indicated in familial abnormal thyroid development

Answer 9

PA8, TTF

Question 10

amiodarone and thyroid

Answer 10

causes hypothyroidism in iodine rich areas

causes hyperthyroidism in iodine poor areas

Question 11

single elevated midnight serum cortisol

Answer 11

suggests Cushings

Question 12

in normal, dexamethasome will suppress

Answer 12

CRH, ACTH, and cortisol

Question 13

low dose dexamethasone test shows

Answer 13

hypercorticalism is present

Question 14

high dose dexamethasone test shows

Answer 14

hypercorticalism is caused by pituitary adenoma or tumor

Question 15

metyrapone stimulation test is for

Answer 15

determining the cause of decreased fortisol

Question 16

best screening test for Cushing

Answer 16

11pm salivary cortisol

Question 17

which pituitary cells produce ACTH

Answer 17

basophilic

Question 18

primary adrenal hypercorticalism in children

Answer 18

more likely due to a carcinoma than adenoma

Question 19

Addison dz =

Answer 19

primary adrenal insufficiency

Question 20

typical lab values in adrenal failure

Answer 20

hypoglycemia
hyponatremia
hyperkalemia
metabolic acidosis

Question 21

cosyntropin test

Answer 21

lack of increase in serum cortisol confirms primary adrenal insuffiency

Question 22

Conn syndrome

Answer 22

hyperaldosteronism

Question 23

secondary hyperaldosteronism seen in

Answer 23

hyper-renin states (renal artery stenosis, juxtaglonerular cell tumor)

Question 24

plasma renin activity measures

Answer 24

conversion of angiotensin I to angiotensin II

Question 25

Renin in primary hyperaldosteonism

Answer 25

low

Question 26

hyperaldosteronism cuases

Answer 26

hypertension
hypervolemia
hypernatremia
hypokalemia
metabolic alkalosis

Question 27

increased ____ seen in 21-hydroxylase def

Answer 27

17-hydroxyprogesterone

Question 28

serum K and Na in 21-hydroxylase def

Answer 28

increased K

decreased Na

Question 29

increased ____ see in 11-hydroxylase def

Answer 29

11-deoxycortisol

Question 30

what is seen in 11-hydroxylase def but not 21-hydroxylase def

Answer 30

Hypertension

Question 31

in borderline cases of CAH, ___ test can be used

Answer 31

corticotrophin stimulation test