Autoimmunity 1 Flashcards by Casey Gooden

Q

ANA homogenous pattern

A

dsDNA, ssDNA, histone

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

ANA rim pattern

A

dsDNA

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

ANA speckled

A

Sm, RNP, Scl70, SS-A/B

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

ANA nucleolar

A

scleroderma

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

ANA centromere

A

CREST

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

ANA cytoplasmic

A

AMA, ASMA

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Anti-dsDNA can be detected by indirect immunoassay using what substrate

A

Crithidia luciliae

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Anti-dsDNA dz

A

SLE

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Anti-histone dz

A

drug-induced lupus

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Anti-Jo1 dz

A

interstitial lung dz in poly/dermatomyositis

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Anti-Sm dz

A

SLE

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Anti-RNP dz

A

mixed connective tissue disease

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Anti-nucleolar dz

A

scleroderma

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

ANti-SSa/b dz

A

sjogren

neonatal lupus

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Anti-mitochondrial dz

A

PBC

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Anti-Liver kidney microsomal dz

A

autoimmune hepatitis

Q

Anti-Smooth muscle dz

A

autoimmune hepatitis

Q

ANti-microsomal dz

A

Hashimoto»>Graves

Q

Anti-endomysial dz

A

celiac, DH

Q

Anti-centromere dz

A

CREST

Q

Anti-IF dz

A

polymyositis/dermatomyositis

Q

Anti-Scl 70 dz

A

progressive systemic sclerosis

Q

cANCA dz

A

Wegener (anti-proteinase 3)

Q

Anti-thyroglobulin dz

A

Hashimoto

Q

Thyroid stimulating Abs dz

A

Graves

Q

Anti-parietal cell dz

A

most sensitive for pernicious anemia

Q

ANti-intrinsic factor dz

A

specific for pernicious anemia

Q

What virtually excludes active SLE

A

negative ANA

Q

Increasing anti-dsDNA predicts

A

SLE flare

Q

ANti-dsDNA and anti-Sm are essentially restricted to

A

SLE

Q

Drugs causing lupus

A

hydralazine, procainamide, isoniazid