Chemistry 16 (Endocrine and Post-Mortem)

Question 1

Pituitary acidophils produce

Answer 1

GH and prolactin

Question 2

Pituitary basophils produce

Answer 2

FSH, LH, ACTH, TSH (B-FLAT)

Question 3

posterior pituitary produces

Answer 3

oxytocin and ADH

Question 4

“prolactin-sparing” hypopituitarism

Answer 4

stalk syndrome

loss of inhibition of prolactin by dopamine

Question 5

GH is inhibited by ___ from ____

Answer 5

somatostatin

pancreas

Question 6

good test for GH excess is

Answer 6

IGF-1

Question 7

when GnRH receptors continuously stimulated

Answer 7

GnRH becomes inhibitory

Question 8

____ inhibits prolactin

Answer 8

dopamine from hypothalamus

Question 9

POMC cleaved into

Answer 9

ACTH, melanocyte stimulating factor, beta-endorphin

Question 10

diabetes insipidus

Answer 10

inadequate ADH

polyuria and polydipisia

Question 11

causes of nephrogenic DI

Answer 11

hypercalcemia
hypokalemia
hypoproteinemia
demeclocycline
lithium

Question 12

hypernatremia with decreased urine osmolality

Answer 12

DI

Question 13

differentiate between central and neprogenic DI

Answer 13

Central: can increase urine osm after ADH admin
Nephrogenic: cannot increase urine osm

Question 14

hyponatremia, normovolemic, increased Urine Na, increased Urine Osm =

Answer 14

SIADH

Question 15

serum glucose ____ after death

Answer 15

increases

Question 16

vitreous glucose ___ after death

Answer 16

decreases

Question 17

preferred sample for postmortem dx of DKA

Answer 17

vitreous

Question 18

dehydration pattern

Answer 18

increased BUN, NA, Cl, Cr

Question 19

normal vitreous KI

Answer 19

<15

Question 20

normal posmortum tryptase

Answer 20

has a high NPV for anaphylaxis