Chemistry 10 (Toxidromes and Alcohols) Flashcards
“hot as a hare” toxidrome effects due to
anticholinergic effects
agents causing anticholinergic toxidrome
atropine, antihistamines, tricyclics, scopolamine
Toxidrome with salivation, lacrimation, urination, diarrhea
cholinergic
agents causing cholinergic toxidrome
organophosphates, pilocarpine, carbamate
toxidrome with HTN, tachycardia, mydriasis, anxiety, hyperthermia
adrenergic
agents causing adrenergic toxidrome
amphetamines, cocaine, epedrine, PCP
toxidrome with AMS, slurred speach, hypopnea/apnea,
sedative/narcotic
agents causing sedative toxidrome
barbiturates, EtOH, opiates
hallucinogenic agenst
LSD, PCP, amphetamines, cocaine
serum osmolarity generally measured by
freezing point depression osmometry
what agents not measured by vapor pressure method
EtOH, methanol
oxygen saturation gap
diff between Co-ox and ABG (nl <5)
increased ox-sat gap caused by
CO, methemoglobin, sulfhemoglobin, cyanide
metabolite of ethylene glycol
oxalate and glycolate
metabolite of isopropyl alcohol
acetone
metabolite of methanol
formaldehyde and formate
anion gap is not present with which alcohol
isopropyl alcohol
which alcohol may increase ketones
EtOH
severe methemoglobinemia may cause pulse ox to give ____ reading
falsely high
mild methemoglobinemia may cuase pulse ox to give _____reading
falsely low
abnormally high venous O2 content
cyanide and hydrogen sulfide
surrogate marker for methanol and ethylene glycol
osmolal gap
correction of osmolal gap for ethanol =
Gap + (EtOH/4.6)
____ is responsible for CNS tox and anion gap acidosis in ethylene glycol
glycolic acid
calcium oxalate crystals found in ___ injestion
ethylene glycol
shape of calcium oxalate crystals
envelope
toxicities of methanol
ocular tox
anion gap acisosis
osmolal gap
isopropyl alcohol is suspected when there is ____ and ____ without ___ or ____
osmolal gap and ketones
without acidosis or anion gap
alternative to EtOH for ethylene glycol and methanol tox
fomepizole