Chemistry 10 (Toxidromes and Alcohols) Flashcards

1
Q

“hot as a hare” toxidrome effects due to

A

anticholinergic effects

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2
Q

agents causing anticholinergic toxidrome

A

atropine, antihistamines, tricyclics, scopolamine

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3
Q

Toxidrome with salivation, lacrimation, urination, diarrhea

A

cholinergic

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4
Q

agents causing cholinergic toxidrome

A

organophosphates, pilocarpine, carbamate

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5
Q

toxidrome with HTN, tachycardia, mydriasis, anxiety, hyperthermia

A

adrenergic

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6
Q

agents causing adrenergic toxidrome

A

amphetamines, cocaine, epedrine, PCP

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7
Q

toxidrome with AMS, slurred speach, hypopnea/apnea,

A

sedative/narcotic

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8
Q

agents causing sedative toxidrome

A

barbiturates, EtOH, opiates

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9
Q

hallucinogenic agenst

A

LSD, PCP, amphetamines, cocaine

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10
Q

serum osmolarity generally measured by

A

freezing point depression osmometry

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11
Q

what agents not measured by vapor pressure method

A

EtOH, methanol

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12
Q

oxygen saturation gap

A

diff between Co-ox and ABG (nl <5)

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13
Q

increased ox-sat gap caused by

A

CO, methemoglobin, sulfhemoglobin, cyanide

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14
Q

metabolite of ethylene glycol

A

oxalate and glycolate

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15
Q

metabolite of isopropyl alcohol

A

acetone

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16
Q

metabolite of methanol

A

formaldehyde and formate

17
Q

anion gap is not present with which alcohol

A

isopropyl alcohol

18
Q

which alcohol may increase ketones

A

EtOH

19
Q

severe methemoglobinemia may cause pulse ox to give ____ reading

A

falsely high

20
Q

mild methemoglobinemia may cuase pulse ox to give _____reading

A

falsely low

21
Q

abnormally high venous O2 content

A

cyanide and hydrogen sulfide

22
Q

surrogate marker for methanol and ethylene glycol

A

osmolal gap

23
Q

correction of osmolal gap for ethanol =

A

Gap + (EtOH/4.6)

24
Q

____ is responsible for CNS tox and anion gap acidosis in ethylene glycol

A

glycolic acid

25
Q

calcium oxalate crystals found in ___ injestion

A

ethylene glycol

26
Q

shape of calcium oxalate crystals

A

envelope

27
Q

toxicities of methanol

A

ocular tox
anion gap acisosis
osmolal gap

28
Q

isopropyl alcohol is suspected when there is ____ and ____ without ___ or ____

A

osmolal gap and ketones

without acidosis or anion gap

29
Q

alternative to EtOH for ethylene glycol and methanol tox

A

fomepizole