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Clinical Pathology > Chemistry 13 (Lipids and Carbs) > Flashcards

Chemistry 13 (Lipids and Carbs) Flashcards

1
Q

Apolopoproteins in chylomicrons

A

B-48, A-1, C, E

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2
Q

function of chylomicrons

A

transport lipid from enterocytes to other cells

endocytosed by apolipoprotein E

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3
Q

apolipoprotein and function of VLDL

A

B-100, C, E

triglycerides to somatic cells

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4
Q

enzymes that hydrolyzes TG in VLDL

A

lipoprotein lipase

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5
Q

Apolipoprotein B-100 present in

A

LDL, IDL, VLDL

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6
Q

HDL apolipoprotein

A

A-1, C, E

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7
Q

Function of LDL

A

transport cholesterol to somatic cells

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8
Q

lecithin cholesterol acyl transferase is present on

A

HDL

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9
Q

VLDL calculation

A

TG/5 (fails if TG>400)

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10
Q

beta-VLDL present in

A

type III dyslipidemia

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11
Q

firedewald equation

A

LDL=Tchol-HDL-TG/5

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12
Q

fiedewald not valid if

A

TG>400
chylomicroms present
type III dyspilidemia

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13
Q

gold standard for LDL measurement

A

ultracentrifugation

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14
Q

lipoprotein electrophoresis bands

A

Chylomicrons don’t move from application point
HDL = alpha
VLDL = pre-beta
LDL = beta

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15
Q

type I dyslipidemia

A

incresed chylommicrons

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16
Q

types IIa and IIb dyslipidemia

A

increased LDL

increased LDL and VLDL

17
Q

type III dyslipidemia

A

increased IDL

18
Q

type V dyslipidemia

A

increased VLDL and chylomicrons

19
Q

apo B is major apolipoprotein of

A

LDL and VLDL

20
Q

tendinous xanthomas present when

A

cholest and TG elevated

21
Q

lipid disorders featuring pancreatitis

A

familial LPL deficiency
apo C-II deficiency
hypertriglyceridemia

22
Q

lipid disorders with very high cholest and TG

A

apolipoprotein E def

familial dysbetalipoproteinemia

23
Q

familial hypercholesterolemia deficiency

A

deficiency of LDL receptor

24
Q

Tangier dz

A

AR

absent HDL

Clinical Pathology (59 decks)

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