fármacos antiobesidad Flashcards

1
Q

Fármacos principales que se usan hoy en día para tratar la obesidad

A
  1. orlistat
  2. liraglutida
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2
Q

MA de rimonabant

A

Inhibidor de CB1

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3
Q

CB1 =

A

Cannabinoid receptors

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4
Q

Efecto farmacológico de rimonabant

A

↓ hambre + peso

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5
Q

Problema principal de rimonabant (+ causa de su retirada del mercado en los 90s)

A

Suicidios

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6
Q

MA de orlistat

A

Inhibición de la lipasa

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7
Q

Efecto farmacológico de orlistat

A

↓ absorción de lípidos

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8
Q

RAMs de orlistat

A
  • malabsorción
  • déficit de vitaminas
  • esteatorrea
  • molestias gastrointestinales
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9
Q

Liraglutida =

A

Análogo (mimético) de GLP-1

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10
Q

Efecto farmacológico de liraglutida

A

Disminuye (suprime) el apetito

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11
Q

RAMs de liraglutida

A
  • molestias gastrointestinales
  • hipoglucemia
  • náuseas
  • diarrea
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12
Q

Otros fármacos anti-obesidad

A
  • lorcaserina
  • fentermina/topiramato
  • naltrexona/bupropion
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