Drug induced liver disease Flashcards

1
Q

Oorzaken van Drug induced liver disease?

A

Lever aandoening veroorzaakt door medicatie
o Alle medicatie kan het veroorzaken
o Paracetamol, amoxi-clav, NSAID’s, antibiotica

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2
Q

Kliniek Drug induced liver disease?

A
  • Algemene klachten: Misselijkheid, asthenie, pruritus, anorexie
  • Symptomen van acute leverfalen
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3
Q

BO Drug induced liver disease?

A

 Labo: verstoorde lever testen, cholestase, afwijkende INR

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4
Q

Behandeling Drug induced liver disease?

A

 Stoppen met medicatie
 Ondersteunende behandeling
 N-Acetylcysteïne voor paracetamol intoxicatie
 Levertransplantatie.

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5
Q

Welke medicatie zorgt voornamelijk voor drug induced liver disease?

A

Paracetamol, amoxi-clav, NSAID’s, antibiotica

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6
Q

Wat is het antidotum voor paracetamolintoxicatie?

A

N-acetylcysteïne

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