Virology Seminar

Question 1

A clinical diagnosis of Erythema Infectiosum is made by the Pediatrician. What infectious agent is responsible for the disease?

A. Human Herpes Virus 6
B. Respiratory Syncytial Virus 
C. Parvovirus B19
D. Paramyxovirus Type 3
E. Rotavirus

Answer 1

C. Parvovirus B19

Question 2

What is the difference in the presentation of parvovirus B19 and roseola?

Answer 2

Roseola will have the rash AFTER the fever breaks while erythema infectiosum will have both concurrently.

Question 3

A similarly aged child, but with history of hereditary spherocytosis, presents with additional symptoms of pallor and fatigue. CBC reveals severe normocytic anemia. Reticulocytes are not detectable in the peripheral blood.
What complication of the above viral infection is this patient manifesting?

A. Iron deficiency anemia
B. Aplastic crisis
C. Hemolytic anemia

Answer 3

B. Aplastic crisis

Question 4

Where can parvovirus B19 replicate that can lead to anemia?

Answer 4

Erythroid precursors in bone marrow

Question 5

What is the most common cause of hospitalization of children under 1 yr?

Answer 5

Bronchiolitis caused by RSV

Question 6

Measles infection in young infants is associated with:

A. A mild disease due to protection by maternal antibody.
B. Atypical measles with rash on the more distal areas of the body.
C. An increased risk for developing SSPE.
D. Prolonged development of Koplik’s spots.

Answer 6

C. An increased risk for developing SSPE - subacute sclerosing panencephalitis

Question 7

The name “pink eye” is obvious. What virus is commonly associated with this clinical presentation?

A. Enterovirus
B. Adenovirus
C. Cytomegalovirus
D. Influenza virus
E. Rhinovirus

Answer 7

B. Adenovirus