Blood Supply of the CNS Flashcards
1
Q
Why are arteries in the CNS more susceptible to HTN related injury?
A
They have quick transitions from large to small - low pressure to high pressure
2
Q
What is unique about the BBB?
A
The capillary endothelial cells adhere to each other with tight junctions and astrocyte end feet surround the endothelium
3
Q
How is the blood supply of the brain regulated?
A
- Metabolic
- Myogenic
4
Q
What is the function of the BBB?
A
Restricts ionic/fluid movements, supplies essential nutrients,
mediates efflux of waste or toxic products
5
Q
What is the composition of the BBB?
A
Capillary endothelial cells - pericytes, astrocytes and neuronal processes
