Schizophrenia

Question 1

Delusions

Answer 1

Unusual thoughts, suspiciousness, strange

thoughts that are out of touch with reality

Question 2

Bizarre Delusions

Answer 2

Clearly implausible, not understandable, and do not derive from ordinary life experiences

Question 3

What are the criteria of schizophrenia?

Answer 3

1. Delusions
2. Hallucinations
3. Disorganized Thinking
4. Disorganized Behavior
5. Negative Symptoms

Question 4

Disorganized Thinking

Answer 4

• Tangential thought process
• Looseness of association or
• Derailment Incoherence or Word salad

Question 5

Disorganized Behavior

Answer 5

• Childlike silliness; unpredictable agitation
• Problems with goal directed behavior
• Inappropriate sexual behavior

Question 6

Negative Symptoms

Answer 6

Loss of certain experiences
– Affective flattening 
– Alogia
– Avolution
– Anhedonia

Question 7

How many criteria are needed for a diagnosis of schizophrenia?

Answer 7

2 criteria are needed but 1 MUST be a delusion, hallucination or disorganized thinking.

Question 8

What are the B criteria for schizophrenia?

Answer 8

Social/Occupational Dysfunction

Question 9

Schizoaffective Disorder

Answer 9

MDD or bipolar with schizophrenia criteria met with a past psychosis episode with no mood symptoms for 2 weeks.

Question 10

Delusional Disorder

Answer 10

Delusions, bizarre or non-bizarre for 1 month with never having met the schizophrenia criteria

Question 11

How can depression seem like schizophrenia?

Answer 11

It can have a lot of the negative symptoms like anhedonia and avolition.

Question 12

What is a major class of drugs that can lead to psychosis?

Answer 12

Steroids

Question 13

Paranoid

Answer 13

Pattern of distrust and suspiciousness of others

Question 14

Schizoid

Answer 14

Social detachment and restricted affect

Question 15

Schizotypal

Answer 15

Odd beliefs, experience or behavior

Question 16

What is the gender prevalence of schizophrenia?

Answer 16

Males and females are equally affected

Question 17

What is the peak age of onset of schizophrenia?

Answer 17

Often in mid to late teens. Women have a second peak in the mid 40s.

Question 18

What is the gender severity of schizophrenia?

Answer 18

More severe in males thought to be due to earlier onset in males and protective effect of estrogen.

Question 19

What is a major risk with schizophrenia?

Answer 19

Suicide risk is increased

Question 20

Wisconsin Card Sort

Answer 20

Schizophrenic patients will make many errors when asked to sort cards according to certain rules.

Question 21

What is the biggest reason for the decrease in life expectancy of schizophrenia patients?

Answer 21

CV disease risk - smoking, diabetes, HTN and hyperlipidemia

Question 22

What is the viral hypothesis of schizophrenia?

Answer 22

There is a higher winter birth rate of schizophrenic patients and association with viral illness that is latent could be likely

Question 23

Is genetics related to schizophrenia?

Answer 23

There is predisposition but it only accounts for 50% of the causes