Histology: Skin Flashcards
What are the layers of the skin?
- Epidermis
- Dermis
- Subcutis
What color does the epidermis stain?
Blue
What color does the dermis stain?
Mostly pink due to the collagen
What makes up the epidermis?
Mostly keratinocytes which makes up the most superficial layer of skin
What are the layers of the epidermis?
- Stratum Corneum
- Stratum Lucidum
- Stratum Granulosum
- Stratum Spinosum
- Stratum Basale
Where is the only place the stratum lucidumis found?
Acral areas - thick skin like on the hands and the soles of the feet
What is found in the stratum granulosum?
Cells contain keratinohyaline granules that stain purple
Where do SCCs arise from?
Stratum Spinosum
Where do BCCs arise from?
Stratum Basale
Where is thin skin found?
Everywhere in the body except acral areas
Where is thick skin found?
Hands and soles of feet
How long does it take for cells to go from the basal layer to the corneal layer?
25 days - this will be decreased in inflammatory conditions
What connects keratinocytes to each other?
Desmosomes
What connects keratinocytes to the basement membrane?
Hemidesmosomes
What is the function of melanocytes?
Produce melanin which is used by the keratinocytes over their nuclei to shield from UV damage
