Clinical Dermatology Flashcards
What is the difference between dermatomyositis and cutaneous lupus?
Cutaneous histology almost identical to acute lupus except frequently more epidermal atrophy
What are the clinical findings with dermatomyositis?
- Violaceous papules on the knuckles (Gottron’s Papules)
- Heliotrope rash on the upper eyelid
- Shawl sign over the upper back that is VERY itchy
What are the clinical findings of cutaneous lupus - acute lupus erythematosis?
- Butterfly rash that spares the nasolabial folds
- Photosensitivity
What is cutaneous lupus highly associated with?
Systemic Lupus Erythematous
What are the clinical features of Discoid Lupus Erythematosus?
- Scarring depressed plaques
- Lichenoid dermatitis with vacuolar interface change
Do most patients with DLE have SLE?
No
What areas of the hand are spared in lupus?
Knuckles
What are the clinical features of scleroderma?
- “Bound‐down” skin
- Sclerodactyly
- Decreasedoral aperture
- May affect other organ systems
- 75% Female
What is CREST syndrome?
More mild scleroderma – Calcinosis cutis – Raynaud’s – Esophageal dysmotility – Sclerodactyly – Telangiectasias
What is the Ab found in CREST?
Anti-centromere Ab
Who does Raynaud’s generally affect?
Women
Raynaud’s Disease
Vasospasm of small vessels with pain and color change
White atrophic plaques that are often associated with localized scleroderma - can be seen in the genital area
Lichen Scelrosus
- Non-caseating granulomas
- Often seen in scars or sites of trauma
- Elevated ACE levels
Sarcoidosis
What is necrobiosis lipoidica associated with?
Diabetes
