Transport Across Cell membranes Flashcards
What are the two main types of membrane proteins that shift molecules in & out the cell?
- Transporters
- Channels
The _______ the molecule & more ________ it is the faster it would move across the bilayer (diffuse rapidly)
The smaller & more nonpolar
Small uncharged _______ molecules diffuse (move quickly) across the bilayer
Polar
Differences in the concentration of inorganic ions across the cell membrane creates a ___________
Membrane Potential
Membrane Potential
Caused by the inbalance of charge ions that create a voltage difference across the membrane
Resting membrane potential
When the movement of anions & cations across the membrane is balanced
The _________ between channels & transporters is how they choose to allow certain molecules to pass through
Difference
___________ choose base on size & charge so only ions of the right size & charge can through it
Channels
________ transfer only molecules or ions that fit into its specific binding site
Transporters
Substances cross the membrane by either ________ or ________ transport
Passive or Active
__________ & _________ allow small, hydrophilic molecules & ions to cross the cell membrane
Transporters & channels
The direction of the molecules whether they move in or out the cell depends on their _________
Concentration
Substances flow from _________ concentrations to _________ concentration
From high concentration to low concentration
Passive Transport
Substance flowing from high concentrations regions to low concentration regions
Active Transport
Carried out by transporters proteins called pumps where they move substance from low concentration to high concentration
Electrochemical Gradient
Osmosis
Water moving across the cell membrane down its concentration gradient (from an area of low solute concentration (high water concentration) to an area of high solute (low water concentration))
Aquaporins
Are specialized channels that speed up the movement of water across the cell membrane
Transporters are responsible for the movement of __________, _________ across the cell membrane
Small water soluble organic molecules & inorganic ions across the cell membrane
___________ move a solute along its eletrochemical gradient
Passive transporters
_________ actively transport a solute against its electrochmeical gradient
Pumps
The _______ pump in animal cells uses energy from ATP to expel ______ & bring in K+
Na+
ATP -driven Na+ pump
Is used in animal cells to remove Na+ out of the cell & bring in K+ into the cell
ATP driven Ca2+ pumps in the plasma membrane & the ER membrane actively remove Ca2+ from the ________
Cytosol
Symport
When the pump moves both solutes in the sam edirection across the membrane
Antiport
When the pump moves the solutes in opposite directions
Uniport
Transporter that move only one type of substance across the membrane
Plants, fungi, & bacteria rely on the ____________ to import solutes into the cell
Electrochemical gradient of H+
Channels form __________ that allow the passive movement of small, water - soluble molecules & ions in or out of the cell
Transmembrane pores
What are the two characterisitcs of ion channels?
- They are ion selectively where they only permit some inorganic ion to pass
- They dont always stay open & some are gated (closed), they can switch between being open & closed
Patch Clamp Recording
Provides a direct picture of how individuals ion channels behave
Different types of gated ion channels respond to different types of stimuli when it stwiches between _________ & ________
Open & Closed
Voltage - gated channel
The probability of being open is controlled by the membrane potential
Ligand - gate channel
Opening is controlled by the binding of some molecule to the channel
Mechanically - gated channel
Opening is controlled by a mechanical force applied to the channel
Neurons
Recieve, integrate, & transmit signals
Nuerons contin _______ which conducts electrical signals away from the cell body toward distant target cells
Axons
Axons allows contain ________ which provides a large surface area to recieve signals from the axons of other neurons
Dendrites
Action Potential
Carries a nerve message without weakening from one end of a neuron to the other end
Action potential are mediated by ___________ channels
Voltage - gated channel
To transmit the neuron message the electrical signal is coverted into a chemical signal celled _____________
Neurooontransmitter
A chemical signal is converted into an electrical signal by ____________ ion channel at a synapse
Postsynoptic transmitter - gated ion channel