Membrane Structure Flashcards
_________ is a barrier to prevent the contents of cells from escaping & mixing with molecules in the surrounding environment & it also allows nutrients to come in & waste to leave
The plasma membrane
_________ is responsible for the structure of all cell membranes
Lipid bilayer
__________ form bilayer in water
Membrane lipids
The types of lipids found in cell membranes are _____________
Phospholipids
Phospholipids
Have a phosphate - containing hydrophillic head linked to a pair of hydrophobic hydrocarbon tails
Amphipathic
Molecules with both hydrophillic & hydrophobic parts
Phospolipids are __________
Amphipathic
What are the two conflicts that happens with amphipathic molecules?
- The hydrphillic head is attracted to water
- The hydrophobic tail shun water
A ________ fixes the conflict in amphipathic molecules where in a ________ the hydrophilic head faces water & the hydrophobic tails are shield from water
Bilayer
When a _________ is form the ________ is quickly fixed (They are self - sealing the amphipathic molecules)
Free edge (tear in the bilayer)
The lipid bilayer is a ___________
Flexible 2-D fluid
____________ spontaneously close in on themselves to form sealed compartments called lipidosomes
Phospholipids bilayers
The _______ of a lipid bilayer depends on its composition
Fluidity
The fluidity of a cell membrane
Is the ease that the lipid molecules move within the bilayer
How _______ a lipid is depends on its phospholipid composition mostly on how packed the hydrocarbon tails are
Fluid
The closer & more packed the hydrocarbon tails the __________ the bilayer is
Less fluid
What are the two major properties that affect how tightly hydrocarbons will pack?
- Their length
- The number of double bonds they contain
The ________ the hydrocarbon tails are they are less likely to interact with one another which increases the fluidity of the bilayer
Shorter
_____________ can form closed, spherical liposomes
Pure Phospholipids
A hydrocarbon tail that contains a __________ is unsaturated
A double bond
A hydrocarbon tail that contain _________ is saturated
Single Bonds
Lipids bilayers that contain large amount of _________ are more fluid than those with small amounts
Double bonds
_________ stiffens cell membranes & prevents light packing of phospholipids
Cholesterol
Membrane assembly begin in the __________
ER (Endoplasmic retriculum)
In ___________ phospholipids are formed in the ER (The cytosolic surface)
Eukaryotic cells
Phospholipids make it to the otherside of the layer by enzymes called __________
Scramblase
Scramblase
Transporter protein that moves randomly selected phospholipids from outer to the inner membrane at the side time moving an inner to the outer membrane
The ________ membrane contains flippases
Gogi membrane
Flippases (Flip Flop movement)
Moves specific phospholipids from the outer side into the inner side of the membrane
__________ helps establish & maintain the asymmetric distribution of the phospholipids characteristic of animal cell membranes
Flippases
_________ have a variety of functions
Plasma membrane proteins
______________ associate with the lipid bilayer in different ways
Membrane proteins
A ___________ chain usually crosses the lipid bilayer as an alpha helix
Polypeptide
__________ are alpha helix because the hydrocarbon side chains are exposed on the outside of the helix where they contact the hydrophobic lipids tails
Polypeptides
Integral membrane proteins
Are permanently bound
Peripheral membrane proteins
Are temporarily bound
Transmembrane proteins
Type of integral membrane proteins & external through the lipid bilayer
___________ bound to other membrane proteins
Peripheral membrane
The backbone of a polypetide chain is _____________
Hydrophilic
A ____________ polypeptide chain usually crosses the lipid bilayer as an alpha helix
Transmembrane
The __________ is reinforced by the underlaying cell cortex
Plasma Membrane
What are some roles of membrane proteins?
- Some transport substances across the lipid bilayer
- Some anchor the membrane to molecules on the outside and inside of the cell
- Some detect chemical signals on the outside and relay them into the cell’s interior
- Some act as enzymes to carry out a reaction near the membrane.