anesthestics Flashcards
1
Q
drugs with ↑ lipid solubility
A
able to cross BBB
↑ potency (more effect with less drug) = 1/MAC
2
Q
minimum concentration of inhaled anesthetic able to achieve anesthesia (not move in response to noxious stimuli) in 50% of subjects
A
minimal alveolar concentration (MAC)
3
Q
3 components to general anesthesia
A
amnesia: no memory
analgesia: pain control
immobilization: paralysis
4
Q
drugs with ↓ blood solubility
A
rapid induction and recovery times
able to leave blood → brain
5
Q
endogenous opioid agonists
A
mu R: B endorphin
delta R: enkphalin
kappa R: dynorphin
