4.11 Brainstem Class Notes Flashcards

1
Q

neuromodulators

A
  • almost always slower

- released upstream of the axon terminal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

neurotransmitters

A
  • fast or slow acting

- released from the presynaptic membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

flat affect in schizos

A
  • too much dopamine being released from SN

- dopamine thought to underlie affect

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which CNs come off the midbrain?

A

3

4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which CNs come off the pons?

A

5
6
7
8

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which CNs come off the medulla?

A

9-12

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

anterior (basilar) brainstem

A

motor (ventral)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

middle (tegmentum) function

A
  • CN function
  • sensory integration
  • reticular formation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

posterior (tectum) function

A

reflexive movements of eyes and head

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

tracts that begin in the brainstem

A
  • rubrospinal
  • reticulospinal
  • vestibulospinal
  • raphespinal
  • ceruleospinal
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the “core” of the brainstem?

A

reticular formation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

RF contains

A
  • reticular nucleu

- ascending & descending reticular pathways

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

3 major functions of RF

A
  • integration of sensory/cortical
  • modulation of nociception
  • regulation of consciousness, motor, autonomic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

4 RF nuclei

A
  1. ventral tegmental area (VTA)
  2. PPN
  3. Raphe nuclei
  4. Locus ceruleus
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

The RF nuclei use (NT/NM)

A

neuromodulators

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

VTA uses this NM

A

dopamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

function of VTA

A
  • reward center
  • motivation
  • decision making
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

targets of VTA

A
  • ventral striatum
  • hippocampus
  • amygdala
  • prefrontal cortex
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

ventral striatum is associated with

A

pleasure and reward

20
Q

hippocampus is associated with

A

memory

21
Q

amygdala is associated with

A
  • emotion

- conversion to long-term memories

22
Q

No dopamine in prefrontal cortex »

A

flat affect

23
Q

NM for PPN

A

acetylcholine

24
Q

function of PPN

A

influences movement (sp. postural muscles)

25
Q

targets of the PPN

A
  • prefrontal cortex
  • motor thalamus
  • GP, STN
  • limbic system
  • origin of RST
26
Q

NM for Raphe nuclei

A

serotonin

27
Q

function of Raphe nuclei

A

modulation of arousal levels

28
Q

Raphe nuclei: midbrain

A

mood (serotonin makes ya happy)

29
Q

Raphe nuclei: pons

A

modulates sensory, autonomic, and motor (more with motivation to move)

30
Q

Raphe nuclei: medulla

A

modulation of pain/sensory

31
Q

Why might people with depression feel pain?

A

due to Raphe nuclei

- interferes with serotonin release onto dorsal horn

32
Q

targets of Raphe nuclei

A
  • cerebral cortex
  • thalamus
  • tectum (MB)
  • striatum
  • amygdala
  • hippocampus
  • SC
33
Q

NM for the locus ceruleus

A

norepinephrine

34
Q

norepinephrine/epi target this

A

hypothalamus (major part of endocrine system)

35
Q

function of locus ceruleus

A

primarily attention (most active during attn)

36
Q

ascending pathways of locus ceruleus

A

direct attn

37
Q

descending pathways of locus ceruleus

A

activation of LMNs + intereurons

38
Q

targets of locus ceruleus

A

similar to serotonin

  • cerebrum
  • thalamus
  • tectum
  • striatum
  • amygdala
  • hippocampus
  • SC
39
Q

ceruleospinal tract function

A

inhibits pain in dorsal horn, natural endorphines - can also use epinephrine

40
Q

What is the locus ceruleus a part of?

A

the ARAS

41
Q

ARAS

A

ascending reticular activating system

42
Q

How does ARAS affect sleep?

A

activation wakes up cerebral cortex

43
Q

What must be the case for normal circadian activity?

A

All parts of the ARAS need to be fully functional

44
Q

internal clock

A

SCN

45
Q

SCN

A

suprachiasmatic nucleus