3.7 PNS stuff 3 Flashcards
3 types of neuropathies
- mononeuropathy
- multiple mononeuropathy
- polyneuropathy
mononeuropathy affects
- single nerve
- focal, one spot
multiple mononeuropathy affects
- several nerves
- multifocal (at least 2 foci)
polyneuropathy affects
many nerves
mononeuropathy causes
- traumatic myelinopathy
- traumatic axonopathy
- traumatic severance
multiple mononeuropathy: s/s
- results in a random constellation of s/s, often due to ischemia
- can happen with diabetes
polyneuropathy movement
- begins distal and moves proximal
- glove and stocking distribution
polyneuropathy pattern
- bilateral
- symmetric
diabetic neuropathy progression and causes
- small blood vessels are damaged first
- high circulating levels of glucose and other inflammatory factors causes
diabetic neuropathy: relationship between blood flow and nerves
equally bad to not have blood flow to the nerves as to other tissue
Why is blood flow so important for nerve health?
deliver nutrients and oxygen to the peripheral nerves
What happens if the nerves are stationary?
axoplasm “globs up” and becomes resistant to movement
Sliding of nerve in the tissue is supported by
- fasciculus plexus
- mesoneurium
fasciculus plexus shares
tension between nerves
movement of nerves facilitates this type of flow
axoplasmic